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Responding to change (a2 only)
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Cell biology
Organisms respond to changes in their internal and external environments (a-level only)
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Britain & the wider world: 1745 -1901
1l the quest for political stability: germany, 1871-1991
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2d religious conflict and the church in england, c1529-c1570
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1f industrialisation and the people: britain, c1783-1885
1c the tudors: england, 1485-1603
2m wars and welfare: britain in transition, 1906-1957
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16 Dec 2025
•
Flo Wood
@flowood
Ever wonder why you shouldn't eat right before a big... Show more





Your body is basically a master of multitasking when it comes to blood flow. At rest, about 80% of your blood goes to organs like your digestive system and kidneys, whilst only 20% reaches your muscles. But the moment you start exercising, this flips completely around.
During exercise, your working muscles demand way more oxygen and nutrients. Your clever cardiovascular system responds by sending 80% of blood flow to these active muscles instead. This redirection happens through the vascular shunt mechanism - think of it as your body's internal traffic management system.
Three types of receptors kick this process into gear: chemoreceptors detect rising CO₂ levels, baroreceptors sense blood pressure changes, and proprioceptors pick up on muscle movement. These all send signals to your vasomotor control centre, which then orchestrates the whole blood redistribution show.
Key Point: This is why you shouldn't eat within an hour of competition - your digestive system will compete with your muscles for blood flow, leaving less available for peak performance.

The magic happens through vasodilation and vasoconstriction - your blood vessels literally changing size to control flow. Arterioles and pre-capillary sphincters are the main players here, acting like adjustable taps throughout your body.
Vasodilation widens the lumen (the opening inside blood vessels) to increase blood flow to working muscles and skin. Meanwhile, vasoconstriction narrows vessels to reduce flow to non-essential areas like your digestive system and kidneys.
Here's what's fascinating: your brain gets exactly the same blood flow whether you're resting or sprinting flat out. Brain function can't be compromised, so it maintains a constant oxygen supply regardless of what else is happening.
Your skin also gets increased blood flow during exercise - not just for oxygen, but to help regulate body temperature through sweating and heat loss to the environment.

The vasomotor centre in your medulla oblongata (part of your brainstem) is mission control for this entire operation. It responds to chemical changes during exercise, particularly increases in CO₂ and lactic acid detected by chemoreceptors.
Sympathetic nerves in blood vessel walls execute the orders. When sympathetic stimulation increases, you get vasoconstriction (smaller lumen). When it decreases, vasodilation occurs (larger lumen). It's like having a remote control for your entire circulatory system.
This mechanism serves several crucial purposes: it increases oxygen supply to muscles, removes waste products like CO₂ and lactic acid, ensures blood reaches your skin for temperature regulation, and directs extra flow to your heart muscle which needs more oxygen to beat faster.
Remember: Your heart is also a muscle that works harder during exercise, so it needs increased blood flow too - that's why cardiac muscle blood flow increases alongside skeletal muscle flow.

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
Flo Wood
@flowood
Ever wonder why you shouldn't eat right before a big match or training session? It's all about how your body cleverly redirects blood flow during exercise. Your cardiovascular system has an amazing ability to redistribute blood away from organs you... Show more

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Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Your body is basically a master of multitasking when it comes to blood flow. At rest, about 80% of your blood goes to organs like your digestive system and kidneys, whilst only 20% reaches your muscles. But the moment you start exercising, this flips completely around.
During exercise, your working muscles demand way more oxygen and nutrients. Your clever cardiovascular system responds by sending 80% of blood flow to these active muscles instead. This redirection happens through the vascular shunt mechanism - think of it as your body's internal traffic management system.
Three types of receptors kick this process into gear: chemoreceptors detect rising CO₂ levels, baroreceptors sense blood pressure changes, and proprioceptors pick up on muscle movement. These all send signals to your vasomotor control centre, which then orchestrates the whole blood redistribution show.
Key Point: This is why you shouldn't eat within an hour of competition - your digestive system will compete with your muscles for blood flow, leaving less available for peak performance.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
The magic happens through vasodilation and vasoconstriction - your blood vessels literally changing size to control flow. Arterioles and pre-capillary sphincters are the main players here, acting like adjustable taps throughout your body.
Vasodilation widens the lumen (the opening inside blood vessels) to increase blood flow to working muscles and skin. Meanwhile, vasoconstriction narrows vessels to reduce flow to non-essential areas like your digestive system and kidneys.
Here's what's fascinating: your brain gets exactly the same blood flow whether you're resting or sprinting flat out. Brain function can't be compromised, so it maintains a constant oxygen supply regardless of what else is happening.
Your skin also gets increased blood flow during exercise - not just for oxygen, but to help regulate body temperature through sweating and heat loss to the environment.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
The vasomotor centre in your medulla oblongata (part of your brainstem) is mission control for this entire operation. It responds to chemical changes during exercise, particularly increases in CO₂ and lactic acid detected by chemoreceptors.
Sympathetic nerves in blood vessel walls execute the orders. When sympathetic stimulation increases, you get vasoconstriction (smaller lumen). When it decreases, vasodilation occurs (larger lumen). It's like having a remote control for your entire circulatory system.
This mechanism serves several crucial purposes: it increases oxygen supply to muscles, removes waste products like CO₂ and lactic acid, ensures blood reaches your skin for temperature regulation, and directs extra flow to your heart muscle which needs more oxygen to beat faster.
Remember: Your heart is also a muscle that works harder during exercise, so it needs increased blood flow too - that's why cardiac muscle blood flow increases alongside skeletal muscle flow.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user