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30 Nov 2025

6 pages

Challenging Biology Topics for Paper 1

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kitty

@kittycooper

Ready to tackle some crucial biology topics that'll pop up... Show more

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# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Microbiology and Digestive System Basics

Ever wondered how scientists grow bacteria in labs without contaminating everything? Aseptic techniques are your best friend here. You'll lift petri dish lids towards a flame to sterilise the air, spread your culture evenly on agar, add antibiotic drops, and incubate at 25°C with partial taping to allow aerobic respiration.

Binary fission is how bacteria reproduce - basically they just split in two. Simple but effective!

Your digestive system is like a food processing factory. Teeth mechanically break down food while amylase in saliva starts chemical breakdown. Your stomach uses hydrochloric acid and enzymes whilst churning everything with muscular walls.

The liver produces bile (stored in the gall bladder) which emulsifies lipids into droplets, increasing surface area for better digestion. The small intestine's duodenum handles carbohydrates and starts on lipids, while the ileum finishes off proteins and carbs, absorbing nutrients into your bloodstream.

Quick Tip: Remember that mechanical digestion physically breaks food down, whilst chemical digestion uses enzymes and acids to break molecular bonds.

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Respiratory System and Heart Function

Your lungs are engineering marvels! Alveoli (tiny air sacs) have massive surface areas for rapid gas exchange. Oxygen diffuses into your bloodstream and binds to haemoglobin in red blood cells, whilst carbon dioxide and water diffuse out.

The pathway goes: trachea → bronchi → bronchioles → alveoli. Think of it like a tree branching out into smaller and smaller tubes.

Your heart runs a double circulatory system - blood enters twice every complete circuit. The right side pumps to your lungs, the left side pumps to your body. The left ventricle has thicker walls because it needs higher pressure to pump blood around your entire body.

Valves prevent backflow, keeping everything moving in the right direction. A group of cells near the right atrium creates electrical pulses that make your heart contract rhythmically.

Remember: The left side of your heart is stronger because it's got a bigger job - pumping blood to your whole body rather than just your lungs!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Plant Structure and Transport Systems

Plants are basically living plumbing systems with two main transport networks. Xylem carries water and minerals upwards from roots to leaves through continuous hollow tubes strengthened by lignin. These are made of dead cells to prevent water loss during transport.

Phloem is the food delivery system, transporting sucrose and amino acids from photosynthesising leaves to non-photosynthesising parts like roots. Unlike xylem, phloem is bidirectional and made of living cells including sieve tubes and companion cells.

Transpiration rate increases with higher temperature, increased air movement, or decreased humidity. Think of it like your plant sweating more on hot, windy days.

Nutrient deficiencies show visible symptoms: nitrate deficiency causes stunted growth, whilst magnesium deficiency leads to chlorosis (yellow leaves) because there's less chlorophyll.

Key Point: Remember that xylem goes UP (water and minerals) whilst phloem goes both ways (sugars and nutrients to wherever they're needed).

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Leaf Structure and Photosynthesis

Leaves are perfectly designed photosynthesis factories. The waxy cuticle prevents water loss, whilst the transparent upper epidermis lets light through to the palisade mesophyll - where most photosynthesis happens thanks to packed chloroplasts.

Spongy mesophyll has gaps for gas exchange, and stomata (controlled by guard cells) regulate gas and water movement. Most stomata are on the lower surface to reduce water loss.

Photosynthesis is an endothermic reaction: water + carbon dioxide → glucose + oxygen. The rate increases with higher temperature, light intensity, or CO₂ levels.

You can measure photosynthesis rates using pondweed - count oxygen bubbles produced at different distances from a light source. Remember the inverse square law: double the distance equals quarter the light intensity.

Exam Tip: Learn the photosynthesis equation properly - it's 6H₂O + 6CO₂ → C₆H₁₂O₆ + 6O₂, and knowing the factors that affect rate will get you easy marks!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Defence Systems and Immune Response

Your body's like a fortress with multiple defence layers. Physical barriers include skin, mucus in your nose and trachea, plus acids and enzymes that kill pathogens. Plants use cell walls, waxy cuticles, bark, thorns, and antibacterial chemicals.

White blood cells are your immune system's soldiers. Lymphocytes produce antibodies that bind to specific antigens on pathogens, plus antitoxins to neutralise toxins. Phagocytes simply engulf and digest pathogens.

The clever bit is immunological memory - once lymphocytes find the right antibody, they store the blueprint in your lymph nodes for future attacks.

Vaccines work by introducing dead or inactive pathogens, letting your body develop immunity without getting ill. It's like giving your immune system a practice run before the real thing.

Think About It: Vaccines are basically immune system training sessions - your body learns to recognise and fight diseases without the nasty symptoms!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s


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iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

 

Biology

93

30 Nov 2025

6 pages

Challenging Biology Topics for Paper 1

user profile picture

kitty

@kittycooper

Ready to tackle some crucial biology topics that'll pop up in your exams? We're diving into everything from growing bacteria cultures to how your heart pumps blood around your body. These concepts might seem complex at first, but once you... Show more

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Microbiology and Digestive System Basics

Ever wondered how scientists grow bacteria in labs without contaminating everything? Aseptic techniques are your best friend here. You'll lift petri dish lids towards a flame to sterilise the air, spread your culture evenly on agar, add antibiotic drops, and incubate at 25°C with partial taping to allow aerobic respiration.

Binary fission is how bacteria reproduce - basically they just split in two. Simple but effective!

Your digestive system is like a food processing factory. Teeth mechanically break down food while amylase in saliva starts chemical breakdown. Your stomach uses hydrochloric acid and enzymes whilst churning everything with muscular walls.

The liver produces bile (stored in the gall bladder) which emulsifies lipids into droplets, increasing surface area for better digestion. The small intestine's duodenum handles carbohydrates and starts on lipids, while the ileum finishes off proteins and carbs, absorbing nutrients into your bloodstream.

Quick Tip: Remember that mechanical digestion physically breaks food down, whilst chemical digestion uses enzymes and acids to break molecular bonds.

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Respiratory System and Heart Function

Your lungs are engineering marvels! Alveoli (tiny air sacs) have massive surface areas for rapid gas exchange. Oxygen diffuses into your bloodstream and binds to haemoglobin in red blood cells, whilst carbon dioxide and water diffuse out.

The pathway goes: trachea → bronchi → bronchioles → alveoli. Think of it like a tree branching out into smaller and smaller tubes.

Your heart runs a double circulatory system - blood enters twice every complete circuit. The right side pumps to your lungs, the left side pumps to your body. The left ventricle has thicker walls because it needs higher pressure to pump blood around your entire body.

Valves prevent backflow, keeping everything moving in the right direction. A group of cells near the right atrium creates electrical pulses that make your heart contract rhythmically.

Remember: The left side of your heart is stronger because it's got a bigger job - pumping blood to your whole body rather than just your lungs!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Plant Structure and Transport Systems

Plants are basically living plumbing systems with two main transport networks. Xylem carries water and minerals upwards from roots to leaves through continuous hollow tubes strengthened by lignin. These are made of dead cells to prevent water loss during transport.

Phloem is the food delivery system, transporting sucrose and amino acids from photosynthesising leaves to non-photosynthesising parts like roots. Unlike xylem, phloem is bidirectional and made of living cells including sieve tubes and companion cells.

Transpiration rate increases with higher temperature, increased air movement, or decreased humidity. Think of it like your plant sweating more on hot, windy days.

Nutrient deficiencies show visible symptoms: nitrate deficiency causes stunted growth, whilst magnesium deficiency leads to chlorosis (yellow leaves) because there's less chlorophyll.

Key Point: Remember that xylem goes UP (water and minerals) whilst phloem goes both ways (sugars and nutrients to wherever they're needed).

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Leaf Structure and Photosynthesis

Leaves are perfectly designed photosynthesis factories. The waxy cuticle prevents water loss, whilst the transparent upper epidermis lets light through to the palisade mesophyll - where most photosynthesis happens thanks to packed chloroplasts.

Spongy mesophyll has gaps for gas exchange, and stomata (controlled by guard cells) regulate gas and water movement. Most stomata are on the lower surface to reduce water loss.

Photosynthesis is an endothermic reaction: water + carbon dioxide → glucose + oxygen. The rate increases with higher temperature, light intensity, or CO₂ levels.

You can measure photosynthesis rates using pondweed - count oxygen bubbles produced at different distances from a light source. Remember the inverse square law: double the distance equals quarter the light intensity.

Exam Tip: Learn the photosynthesis equation properly - it's 6H₂O + 6CO₂ → C₆H₁₂O₆ + 6O₂, and knowing the factors that affect rate will get you easy marks!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Defence Systems and Immune Response

Your body's like a fortress with multiple defence layers. Physical barriers include skin, mucus in your nose and trachea, plus acids and enzymes that kill pathogens. Plants use cell walls, waxy cuticles, bark, thorns, and antibacterial chemicals.

White blood cells are your immune system's soldiers. Lymphocytes produce antibodies that bind to specific antigens on pathogens, plus antitoxins to neutralise toxins. Phagocytes simply engulf and digest pathogens.

The clever bit is immunological memory - once lymphocytes find the right antibody, they store the blueprint in your lymph nodes for future attacks.

Vaccines work by introducing dead or inactive pathogens, letting your body develop immunity without getting ill. It's like giving your immune system a practice run before the real thing.

Think About It: Vaccines are basically immune system training sessions - your body learns to recognise and fight diseases without the nasty symptoms!

# microbiology
Bacteria reproduce b
binary fission

making cultures with aseptic
techniques:
1-Lift the lid of petridish
towards flame (to s

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

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Most popular content: Antibodies

Most popular content in Biology

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Can't find what you're looking for? Explore other subjects.

Students love us — and so will you.

4.9/5

App Store

4.8/5

Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user