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2 Dec 2025

842

4 pages

Biology Paper 1 – Comprehensive Guide for Combined Science

user profile picture

lima @lima_gbpl

The heart and human body cells work together as a remarkable biological system. This summary explores how the... Show more

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

The Heart and Circulatory System

Your heart is a pumping organ that keeps blood flowing throughout your body. Its special valves ensure blood flows in the correct direction and prevent it from flowing backwards. The heart has four chambers left atrium, left ventricle, right atrium, and right ventricle.

Blood enters the heart through the vena cava and pulmonary vein into the atria. When the atria contract, blood is forced into the ventricles. The ventricles then push blood out through the pulmonary artery and aorta. This creates a continuous cycle as blood flows to organs through arteries and returns through veins.

The heart needs its own blood supply to function. Coronary arteries branch from the aorta and surround the heart, providing it with the oxygenated blood it needs. Other important blood vessels include arteries (which carry blood away from the heart), capillaries (where exchange occurs at tissues), and veins (which return blood to the heart).

Did you know? The heart has its own natural pacemaker! A special group of cells in the right atrium produces electrical impulses that control the heart's rhythm. Some people need artificial pacemakers to help their hearts beat regularly.

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Cell Division and Stem Cells

Your body contains cells with 46 chromosomes arranged in 23 pairs (half from mum, half from dad). The cell cycle, which takes less than 24 hours, involves mitosis to produce two identical daughter cells. During this process, the genetic material is doubled to ensure each new cell gets a complete set of chromosomes.

Stem cells are undifferentiated cells that can develop into many different cell types. They're incredibly important for growth and development. In humans, egg and sperm cells fuse to form a zygote (a single cell), which then divides and becomes an embryo. The cell cycle has three main stages growth and DNA replication, division of chromosomes, and division of cytoplasm and cell membrane.

Stem cells have enormous potential for medicine and research. In plants, they can be used to produce clones quickly, which helps preserve rare species from extinction. Scientists can also use them to study how genetic changes affect development.

Important! Enzymes are biological catalysts that control chemical reactions in living organisms. Their specific shape allows them to join with substrate molecules, which is vital for their function.

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Food Testing Methods

You can identify different food molecules through simple chemical tests. The general preparation involves grinding up food, mixing it with distilled water, stirring well, and filtering to remove solid bits before testing.

The Benedict's test identifies reducing sugars. After preparing 5cm³ of food sample in a test tube, heat it to 75°C in a water bath with Benedict's solution for 5 minutes. If reducing sugars are present, the solution changes from blue to green, yellow, or brick red depending on concentration.

For starch, use the iodine test - add a few drops of iodine solution to 5cm³ of food sample and gently shake. The solution will change from brownish-orange to black or dark blue if starch is present. The Biuret test identifies proteins - add 2cm³ of Biuret solution to your sample and if it turns from blue to purple, proteins are present. To test for lipids, use the Sudan III test - add 3 drops to your sample and if lipids are present, the mixture separates into two layers with the top layer turning red.

Exam tip Remember the specific color changes for each test - they're commonly asked about in assessments and practical exams!

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Cell Structure and Functions

Both plant and animal cells are eukaryotic cells with important structures. Plant cells have additional features like a cell wall, chloroplasts, and a permanent vacuole. Animal cells contain a cell membrane, cytoplasm, nucleus, and mitochondria. The nucleus controls cell function and contains genetic material, while mitochondria are where aerobic respiration takes place.

Specialized cells have adapted structures for specific functions. Sperm cells have a long tail to swim, mitochondria for energy, and an acrosome with digestive enzymes. Root hair cells help plants absorb water and minerals through their large surface area. Nerve cells have long axons for transmitting electrical impulses and form synapses (gaps where neurons meet).

Diffusion is the spreading of particles from areas of high concentration to low concentration. Osmosis is specifically the movement of water molecules across a partially permeable membrane. In plants, osmosis creates turgor pressure which makes cells rigid and supports stems and leaves.

Connect the dots The transport systems in plants work much like your circulatory system. Phloem tissue transports food made during photosynthesis throughout the plant, similar to how blood carries nutrients around your body.

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This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

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Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

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Thomas R

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Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

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This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

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In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

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very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

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I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

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THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

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Paul T

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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

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This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

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Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

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Best app on earth! no words because it’s too good

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Xander S

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Biology

842

2 Dec 2025

4 pages

Biology Paper 1 – Comprehensive Guide for Combined Science

user profile picture

lima

@lima_gbpl

The heart and human body cells work together as a remarkable biological system. This summary explores how the heart pumps blood throughout the body, the process of cell division, food testing methods, and the structure of different cell types. Understanding... Show more

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

The Heart and Circulatory System

Your heart is a pumping organ that keeps blood flowing throughout your body. Its special valves ensure blood flows in the correct direction and prevent it from flowing backwards. The heart has four chambers: left atrium, left ventricle, right atrium, and right ventricle.

Blood enters the heart through the vena cava and pulmonary vein into the atria. When the atria contract, blood is forced into the ventricles. The ventricles then push blood out through the pulmonary artery and aorta. This creates a continuous cycle as blood flows to organs through arteries and returns through veins.

The heart needs its own blood supply to function. Coronary arteries branch from the aorta and surround the heart, providing it with the oxygenated blood it needs. Other important blood vessels include arteries (which carry blood away from the heart), capillaries (where exchange occurs at tissues), and veins (which return blood to the heart).

Did you know? The heart has its own natural pacemaker! A special group of cells in the right atrium produces electrical impulses that control the heart's rhythm. Some people need artificial pacemakers to help their hearts beat regularly.

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Cell Division and Stem Cells

Your body contains cells with 46 chromosomes arranged in 23 pairs (half from mum, half from dad). The cell cycle, which takes less than 24 hours, involves mitosis to produce two identical daughter cells. During this process, the genetic material is doubled to ensure each new cell gets a complete set of chromosomes.

Stem cells are undifferentiated cells that can develop into many different cell types. They're incredibly important for growth and development. In humans, egg and sperm cells fuse to form a zygote (a single cell), which then divides and becomes an embryo. The cell cycle has three main stages: growth and DNA replication, division of chromosomes, and division of cytoplasm and cell membrane.

Stem cells have enormous potential for medicine and research. In plants, they can be used to produce clones quickly, which helps preserve rare species from extinction. Scientists can also use them to study how genetic changes affect development.

Important! Enzymes are biological catalysts that control chemical reactions in living organisms. Their specific shape allows them to join with substrate molecules, which is vital for their function.

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Food Testing Methods

You can identify different food molecules through simple chemical tests. The general preparation involves grinding up food, mixing it with distilled water, stirring well, and filtering to remove solid bits before testing.

The Benedict's test identifies reducing sugars. After preparing 5cm³ of food sample in a test tube, heat it to 75°C in a water bath with Benedict's solution for 5 minutes. If reducing sugars are present, the solution changes from blue to green, yellow, or brick red depending on concentration.

For starch, use the iodine test - add a few drops of iodine solution to 5cm³ of food sample and gently shake. The solution will change from brownish-orange to black or dark blue if starch is present. The Biuret test identifies proteins - add 2cm³ of Biuret solution to your sample and if it turns from blue to purple, proteins are present. To test for lipids, use the Sudan III test - add 3 drops to your sample and if lipids are present, the mixture separates into two layers with the top layer turning red.

Exam tip: Remember the specific color changes for each test - they're commonly asked about in assessments and practical exams!

around the body.
The heart is pumping
organ which keeps blood
Having
Valres-make sure blood
Plows in correct direction.
(prevent flouring ba

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Cell Structure and Functions

Both plant and animal cells are eukaryotic cells with important structures. Plant cells have additional features like a cell wall, chloroplasts, and a permanent vacuole. Animal cells contain a cell membrane, cytoplasm, nucleus, and mitochondria. The nucleus controls cell function and contains genetic material, while mitochondria are where aerobic respiration takes place.

Specialized cells have adapted structures for specific functions. Sperm cells have a long tail to swim, mitochondria for energy, and an acrosome with digestive enzymes. Root hair cells help plants absorb water and minerals through their large surface area. Nerve cells have long axons for transmitting electrical impulses and form synapses (gaps where neurons meet).

Diffusion is the spreading of particles from areas of high concentration to low concentration. Osmosis is specifically the movement of water molecules across a partially permeable membrane. In plants, osmosis creates turgor pressure which makes cells rigid and supports stems and leaves.

Connect the dots: The transport systems in plants work much like your circulatory system. Phloem tissue transports food made during photosynthesis throughout the plant, similar to how blood carries nutrients around your body.

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

7

Smart Tools NEW

Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines

Mock Exam
Quiz
Flashcards
Essay

Similar content

Cell Differentiation & Division

Explore the processes of cell differentiation, the cell cycle, mitosis, and meiosis. Understand the roles of stem cells, their potency, and the significance of specialized cells like erythrocytes and neutrophils. This summary also addresses ethical concerns surrounding stem cell use and highlights the organization of cells into tissues and organs.

BiologyBiology
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Explore the detailed stages of mitosis, including Prophase, Metaphase, Anaphase, and Telophase. This summary highlights key events such as chromatin condensation, spindle apparatus formation, and cytokinesis, essential for A Level Biology students. Understand the cell cycle phases and their significance in cell division.

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Explore the essential processes of photosynthesis, including the role of chlorophyll, light-dependent reactions, and factors affecting plant growth. This summary covers the conversion of carbon dioxide and water into glucose, the importance of light, and adaptations of leaves for optimal photosynthesis. Ideal for GCSE Biology students seeking to understand plant productivity and the significance of photosynthesis in ecosystems.

BiologyBiology
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Mitosis Phases Explained

Explore the stages of mitosis in detail, including interphase, prophase, metaphase, anaphase, and telophase. This concise summary highlights the key processes involved in cell division, essential for GCSE Edexcel and AQA students. Understand how mitosis contributes to growth and cell replacement, and use the PMAT acronym to remember the sequence of events.

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Most popular content: Heart

Most popular content in Biology

Most popular content

Can't find what you're looking for? Explore other subjects.

Students love us — and so will you.

4.9/5

App Store

4.8/5

Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user