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6 Dec 2025
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Understanding the Cell Cycle: Mitosis and Meiosis Explained
M
@iamjungkook
1 / 8
Interphase: The Cell's Prep Time
Think of interphase as the longest "behind-the-scenes" stage where cells get ready for division. It's actually the most active time in a cell's life, not a resting period like you might think.
The cell goes through three phases: G1 (growth), S (synthesis), and G2 (more growth). During G1, your cell doubles in size and churns out proteins and organelles. The S phase is where the magic happens - DNA gets copied so each chromosome becomes two identical sister chromatids.
Checkpoints act like quality control inspectors throughout interphase. They check if the cell is big enough, has enough nutrients, and whether the DNA is healthy before allowing division to continue. If something's not right, the cell gets sent to G0 - basically a dormant waiting room where it can stay for weeks or even years.
Key Point: Cells spend about 90% of their time in interphase, making it the most important stage of the cell cycle.
Mitosis: Creating Identical Copies
Mitosis is your body's photocopier - it creates two genetically identical diploid cells from one parent cell. This process happens in all your somatic cells (basically every cell except sperm and eggs) and is essential for growth and replacing damaged tissue.
Before mitosis kicks off, each chromosome consists of two sister chromatids joined at the centromere. These are exact copies of each other, ready to be split between the two new daughter cells.
Mitosis enables everything from healing a cut on your finger to growing from a tiny embryo into a full-sized human. Single-celled organisms also use it for asexual reproduction - essentially cloning themselves.
Remember: Prokaryotes (bacteria) can't do mitosis because they lack a nucleus - they use binary fission instead.
PMAT: The Four Stages of Mitosis
Remember PMAT - it'll save you in exams! Each stage has a specific job in dividing the cell properly.
Prophase is when things get serious - the nuclear envelope breaks down, spindle fibres form from the centrioles, and chromosomes condense into visible, chunky structures. Think of it as the cell's preparation phase.
Metaphase is the organisation stage. Chromosomes line up perfectly at the cell's equator (the metaphase plate) with spindle fibres attached to each centromere. This alignment is crucial - any mistakes here lead to problems.
Visual Tip: In metaphase, chromosomes look like they're doing a perfectly choreographed dance routine, all lined up in the middle.
Anaphase and Telophase: The Final Split
Anaphase is where the real action happens - centromeres split and sister chromatids get yanked to opposite poles of the cell. They move centromere-first, creating that distinctive V-shape you'll see in diagrams.
Telophase essentially reverses prophase. New nuclear envelopes form around each group of chromosomes, which start to uncoil back into their stringy form. The spindle fibres disappear, and two nuclei emerge.
Cytokinesis is the final physical split. In animal cells, a cleavage furrow pinches the cell in two. Plant cells build a new cell wall down the middle instead - they can't pinch because of their rigid cell walls.
End Result: Two identical diploid daughter cells, each with exactly the same genetic information as the parent.
Meiosis: Creating Genetic Diversity
Meiosis is completely different from mitosis - it's all about creating gametes (sex cells) that are genetically unique. This process maintains constant chromosome numbers across generations and promotes genetic diversity through some clever molecular shuffling.
Unlike mitosis, meiosis involves two rounds of division: Meiosis I and Meiosis II. The whole process starts with the same interphase as mitosis, where DNA gets replicated.
Prophase I is where the excitement begins. Homologous chromosomes (one from mum, one from dad) pair up and perform crossing over - they literally swap sections of genetic material. This creates new combinations of alleles that didn't exist in either parent.
Key Concept: Homologous chromosomes contain the same genes but different versions (alleles) of each gene.
Meiosis Continues: Two Divisions, Four Cells
Metaphase I and Anaphase I create the first major difference from mitosis. Homologous pairs line up randomly at the equator (independent assortment), then whole chromosomes (not sister chromatids) get pulled apart. This random arrangement creates even more genetic variation.
Telophase I produces two haploid cells, each with half the original chromosome number. But we're not done yet - Meiosis II follows immediately.
Meiosis II looks just like mitosis but with haploid cells. The sister chromatids finally separate, producing four genetically unique haploid gametes from one original diploid cell.
Bottom Line: Meiosis turns one diploid cell into four genetically different haploid cells - perfect for sexual reproduction.
Stem Cells: The Body's Repair Kit
Stem cells are your body's ultimate multitaskers - undifferentiated cells that can become almost any cell type through differentiation. Once they specialise, there's no going back.
Potency describes a stem cell's flexibility. Totipotent cells (from early embryos) can become anything, including a whole organism. Pluripotent cells can form any tissue but not entire organisms. Multipotent cells are more limited - like bone marrow stem cells that only make blood cells.
Your bone marrow works overtime, producing 3 billion red blood cells daily just to keep up with demand. Some white blood cells only last 6 hours, so this production never stops.
Medical Marvel: Stem cell therapy shows promise for treating heart attacks, diabetes, Parkinson's, and other diseases by replacing damaged cells.
Genetic Variation: Nature's Lottery System
Two key mechanisms create genetic diversity during meiosis: crossing over and independent assortment. Both ensure that no two gametes (except identical twins) are ever genetically identical.
Crossing over happens when non-sister chromatids swap genetic material during Prophase I. This creates new allele combinations that never existed in either parent - it's like shuffling a deck of cards.
Independent assortment occurs because chromosome pairs align randomly during Metaphase I. Maternal and paternal chromosomes face either pole randomly, creating millions of possible combinations in the resulting gametes.
Mind-Blowing Fact: These processes mean you could theoretically produce over 8 million genetically different gametes - and that's before considering crossing over!
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Elisha
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This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
Understanding the Cell Cycle: Mitosis and Meiosis Explained
M
@iamjungkook
Cell division is how your body grows from a single fertilised egg into a complex multicellular organism. There are two main types: mitosis creates identical cells for growth and repair, whilst meiosis produces genetically diverse sex cells for reproduction.
Interphase: The Cell's Prep Time
Think of interphase as the longest "behind-the-scenes" stage where cells get ready for division. It's actually the most active time in a cell's life, not a resting period like you might think.
The cell goes through three phases: G1 (growth), S (synthesis), and G2 (more growth). During G1, your cell doubles in size and churns out proteins and organelles. The S phase is where the magic happens - DNA gets copied so each chromosome becomes two identical sister chromatids.
Checkpoints act like quality control inspectors throughout interphase. They check if the cell is big enough, has enough nutrients, and whether the DNA is healthy before allowing division to continue. If something's not right, the cell gets sent to G0 - basically a dormant waiting room where it can stay for weeks or even years.
Key Point: Cells spend about 90% of their time in interphase, making it the most important stage of the cell cycle.
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Mitosis: Creating Identical Copies
Mitosis is your body's photocopier - it creates two genetically identical diploid cells from one parent cell. This process happens in all your somatic cells (basically every cell except sperm and eggs) and is essential for growth and replacing damaged tissue.
Before mitosis kicks off, each chromosome consists of two sister chromatids joined at the centromere. These are exact copies of each other, ready to be split between the two new daughter cells.
Mitosis enables everything from healing a cut on your finger to growing from a tiny embryo into a full-sized human. Single-celled organisms also use it for asexual reproduction - essentially cloning themselves.
Remember: Prokaryotes (bacteria) can't do mitosis because they lack a nucleus - they use binary fission instead.
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PMAT: The Four Stages of Mitosis
Remember PMAT - it'll save you in exams! Each stage has a specific job in dividing the cell properly.
Prophase is when things get serious - the nuclear envelope breaks down, spindle fibres form from the centrioles, and chromosomes condense into visible, chunky structures. Think of it as the cell's preparation phase.
Metaphase is the organisation stage. Chromosomes line up perfectly at the cell's equator (the metaphase plate) with spindle fibres attached to each centromere. This alignment is crucial - any mistakes here lead to problems.
Visual Tip: In metaphase, chromosomes look like they're doing a perfectly choreographed dance routine, all lined up in the middle.
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Anaphase and Telophase: The Final Split
Anaphase is where the real action happens - centromeres split and sister chromatids get yanked to opposite poles of the cell. They move centromere-first, creating that distinctive V-shape you'll see in diagrams.
Telophase essentially reverses prophase. New nuclear envelopes form around each group of chromosomes, which start to uncoil back into their stringy form. The spindle fibres disappear, and two nuclei emerge.
Cytokinesis is the final physical split. In animal cells, a cleavage furrow pinches the cell in two. Plant cells build a new cell wall down the middle instead - they can't pinch because of their rigid cell walls.
End Result: Two identical diploid daughter cells, each with exactly the same genetic information as the parent.
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Meiosis: Creating Genetic Diversity
Meiosis is completely different from mitosis - it's all about creating gametes (sex cells) that are genetically unique. This process maintains constant chromosome numbers across generations and promotes genetic diversity through some clever molecular shuffling.
Unlike mitosis, meiosis involves two rounds of division: Meiosis I and Meiosis II. The whole process starts with the same interphase as mitosis, where DNA gets replicated.
Prophase I is where the excitement begins. Homologous chromosomes (one from mum, one from dad) pair up and perform crossing over - they literally swap sections of genetic material. This creates new combinations of alleles that didn't exist in either parent.
Key Concept: Homologous chromosomes contain the same genes but different versions (alleles) of each gene.
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Meiosis Continues: Two Divisions, Four Cells
Metaphase I and Anaphase I create the first major difference from mitosis. Homologous pairs line up randomly at the equator (independent assortment), then whole chromosomes (not sister chromatids) get pulled apart. This random arrangement creates even more genetic variation.
Telophase I produces two haploid cells, each with half the original chromosome number. But we're not done yet - Meiosis II follows immediately.
Meiosis II looks just like mitosis but with haploid cells. The sister chromatids finally separate, producing four genetically unique haploid gametes from one original diploid cell.
Bottom Line: Meiosis turns one diploid cell into four genetically different haploid cells - perfect for sexual reproduction.
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Stem Cells: The Body's Repair Kit
Stem cells are your body's ultimate multitaskers - undifferentiated cells that can become almost any cell type through differentiation. Once they specialise, there's no going back.
Potency describes a stem cell's flexibility. Totipotent cells (from early embryos) can become anything, including a whole organism. Pluripotent cells can form any tissue but not entire organisms. Multipotent cells are more limited - like bone marrow stem cells that only make blood cells.
Your bone marrow works overtime, producing 3 billion red blood cells daily just to keep up with demand. Some white blood cells only last 6 hours, so this production never stops.
Medical Marvel: Stem cell therapy shows promise for treating heart attacks, diabetes, Parkinson's, and other diseases by replacing damaged cells.
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Genetic Variation: Nature's Lottery System
Two key mechanisms create genetic diversity during meiosis: crossing over and independent assortment. Both ensure that no two gametes (except identical twins) are ever genetically identical.
Crossing over happens when non-sister chromatids swap genetic material during Prophase I. This creates new allele combinations that never existed in either parent - it's like shuffling a deck of cards.
Independent assortment occurs because chromosome pairs align randomly during Metaphase I. Maternal and paternal chromosomes face either pole randomly, creating millions of possible combinations in the resulting gametes.
Mind-Blowing Fact: These processes mean you could theoretically produce over 8 million genetically different gametes - and that's before considering crossing over!
We thought you’d never ask...
What is the Knowunity AI companion?
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
Where can I download the Knowunity app?
You can download the app from Google Play Store and Apple App Store.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user