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Responding to change (a2 only)
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Cell biology
Organisms respond to changes in their internal and external environments (a-level only)
Biological molecules
Organisation
Substance exchange
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Cells
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1f industrialisation and the people: britain, c1783-1885
1c the tudors: england, 1485-1603
2m wars and welfare: britain in transition, 1906-1957
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1
0
mollie
12/12/2025
Biology
CCEA AS Biology Unit 1- Cell Physiology
51
•
12 Dec 2025
•
mollie
@molliegilmore_xwcx
Ever wondered how substances get in and out of cells?... Show more










Your cells are constantly moving substances around, and simple diffusion is the most basic way this happens. Think of it like a crowded room where people naturally spread out - molecules move from areas of high concentration to low concentration without any energy needed.
This passive process relies on the natural kinetic energy of molecules bouncing around. The rate gets faster with higher temperatures, thinner surfaces, and larger surface areas - just like how heat makes molecules move more quickly.
Facilitated diffusion works similarly but uses special proteins as helpers. Channel proteins act like selective doorways for ions, whilst carrier proteins change shape to transport larger molecules across the cell membrane.
Key Point: Both simple and facilitated diffusion are passive - they don't require energy from the cell!

Channel proteins are like water-filled tunnels that allow specific ions to pass through the cell membrane. They're highly selective - each channel only allows one type of ion through, and they can be opened or closed like gates when they receive the right signal.
Carrier proteins handle the bigger jobs, transporting larger ions and polar molecules. When a molecule binds to the carrier, the protein changes shape to move it across the membrane - it's like a revolving door that flips the molecule to the other side.
Understanding hypotonic and hypertonic solutions is crucial here. These terms describe the concentration differences that drive all these transport processes.
Remember: Channel proteins are for small ions, carrier proteins are for larger molecules!

Sometimes cells need to move substances uphill, from low concentration to high concentration - that's where active transport comes in. Unlike passive processes, this requires energy in the form of ATP, which means cells need lots of mitochondria to power it.
The process works through specific protein carriers that span the membrane. These proteins accept molecules, change shape to transport them, then react with ATP to get the energy needed for the job.
Anything that increases respiration - like higher temperature or exercise - will boost active transport rates. That's because more respiration means more ATP production, giving cells more energy to power these uphill journeys.
Energy Fact: Active transport is like pushing a boulder uphill - it takes serious cellular energy!

When molecules are too large for protein carriers, cells use cytosis - transport via vesicles (tiny membrane bubbles). This process can handle massive molecules or even transport smaller ones in bulk.
There are two main types: endocytosis (bringing material into the cell) and exocytosis (moving material out). During endocytosis, the cell surface membrane invaginates (folds inward), pinches off, and forms a vesicle containing the material.
The process is like the cell's mouth - it can 'eat' particles by wrapping membrane around them and pulling them inside.
Size Matters: When regular transport proteins can't handle the job, cytosis takes over!

Phagocytosis handles solid materials - the cell membrane wraps around particles, forms vesicles, then digests the contents with enzymes. Pinocytosis does the same job but for liquids, creating smaller vesicles.
Exocytosis works in reverse - vesicles move toward the cell surface, fuse with the membrane, open up, and release their contents outside.
Osmosis is the net movement of water from high water potential to low water potential across a selectively permeable membrane. Water moves through specialised aquaporins - protein channels designed specifically for water molecules.
Water Transport: Aquaporins are like express lanes just for water molecules!

Water potential measures a solution's tendency to take in water by osmosis, expressed in kilopascals (kPa). Pure water has a water potential of 0 kPa because all water molecules are free to move.
When solutes are added, water potential becomes more negative because some water molecules form hydration shells around the solutes. The more concentrated a solution, the more negative its water potential becomes.
Here's the key: higher water potential means a less negative number, whilst lower water potential means a more negative number. A solution with -600 kPa will take in less water than one with -1000 kPa.
Think Negative: More concentrated = more negative water potential!

Plant cells have two components affecting water movement: solute potential (Ψs) relates to solute concentration only, whilst pressure potential (Ψp) is the effect of pressure on the solution. The formula is: Ψcell = Ψs + Ψp.
In hypotonic solutions, plant cell vacuoles increase in size, pushing the cell membrane against the cell wall and creating turgor pressure. This turgidity gives plants structural support - it's why plants wilt when they lack water.
Pressure potential should be positive and varies from 0 in fully plasmolysed cells to maximum in turgid cells.
Plant Support: Turgor pressure is what keeps plants standing upright!

In hypertonic solutions, plant cell vacuoles shrink, pulling the cell membrane away from the wall - this process is called plasmolysis. The cell loses its structural support and becomes floppy.
Isotonic solutions create equilibrium with equal amounts of water entering and leaving the cell. This state is called incipient plasmolysis, where the membrane begins to lose contact with the cell wall.
You can observe three distinct states: plasmolysed (shrunken), flaccid (limp), and turgid (firm and upright).
Plant Health Check: Turgid = healthy, plasmolysed = dehydrated!

Animal cells face greater osmotic challenges because they lack protective cell walls. In hypotonic solutions, water enters animal cells, and if too much gets in, the cells burst - this destructive process is called cell lysis.
In hypertonic solutions, water leaves animal cells, causing them to shrink and shrivel up. This is why maintaining proper fluid balance is crucial for animal survival.
Unlike plant cells that can benefit from some water pressure, animal cells need to maintain careful water balance to avoid damage.
No Protection: Without cell walls, animal cells are more vulnerable to osmotic damage!
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You can download the app from Google Play Store and Apple App Store.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
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This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
mollie
@molliegilmore_xwcx
Ever wondered how substances get in and out of cells? Cell physiology is all about the different transport methods that keep your cells alive and functioning. From simple diffusion to complex active transport, these processes are happening in your body... Show more

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Your cells are constantly moving substances around, and simple diffusion is the most basic way this happens. Think of it like a crowded room where people naturally spread out - molecules move from areas of high concentration to low concentration without any energy needed.
This passive process relies on the natural kinetic energy of molecules bouncing around. The rate gets faster with higher temperatures, thinner surfaces, and larger surface areas - just like how heat makes molecules move more quickly.
Facilitated diffusion works similarly but uses special proteins as helpers. Channel proteins act like selective doorways for ions, whilst carrier proteins change shape to transport larger molecules across the cell membrane.
Key Point: Both simple and facilitated diffusion are passive - they don't require energy from the cell!

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Channel proteins are like water-filled tunnels that allow specific ions to pass through the cell membrane. They're highly selective - each channel only allows one type of ion through, and they can be opened or closed like gates when they receive the right signal.
Carrier proteins handle the bigger jobs, transporting larger ions and polar molecules. When a molecule binds to the carrier, the protein changes shape to move it across the membrane - it's like a revolving door that flips the molecule to the other side.
Understanding hypotonic and hypertonic solutions is crucial here. These terms describe the concentration differences that drive all these transport processes.
Remember: Channel proteins are for small ions, carrier proteins are for larger molecules!

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Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Sometimes cells need to move substances uphill, from low concentration to high concentration - that's where active transport comes in. Unlike passive processes, this requires energy in the form of ATP, which means cells need lots of mitochondria to power it.
The process works through specific protein carriers that span the membrane. These proteins accept molecules, change shape to transport them, then react with ATP to get the energy needed for the job.
Anything that increases respiration - like higher temperature or exercise - will boost active transport rates. That's because more respiration means more ATP production, giving cells more energy to power these uphill journeys.
Energy Fact: Active transport is like pushing a boulder uphill - it takes serious cellular energy!

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When molecules are too large for protein carriers, cells use cytosis - transport via vesicles (tiny membrane bubbles). This process can handle massive molecules or even transport smaller ones in bulk.
There are two main types: endocytosis (bringing material into the cell) and exocytosis (moving material out). During endocytosis, the cell surface membrane invaginates (folds inward), pinches off, and forms a vesicle containing the material.
The process is like the cell's mouth - it can 'eat' particles by wrapping membrane around them and pulling them inside.
Size Matters: When regular transport proteins can't handle the job, cytosis takes over!

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Phagocytosis handles solid materials - the cell membrane wraps around particles, forms vesicles, then digests the contents with enzymes. Pinocytosis does the same job but for liquids, creating smaller vesicles.
Exocytosis works in reverse - vesicles move toward the cell surface, fuse with the membrane, open up, and release their contents outside.
Osmosis is the net movement of water from high water potential to low water potential across a selectively permeable membrane. Water moves through specialised aquaporins - protein channels designed specifically for water molecules.
Water Transport: Aquaporins are like express lanes just for water molecules!

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Water potential measures a solution's tendency to take in water by osmosis, expressed in kilopascals (kPa). Pure water has a water potential of 0 kPa because all water molecules are free to move.
When solutes are added, water potential becomes more negative because some water molecules form hydration shells around the solutes. The more concentrated a solution, the more negative its water potential becomes.
Here's the key: higher water potential means a less negative number, whilst lower water potential means a more negative number. A solution with -600 kPa will take in less water than one with -1000 kPa.
Think Negative: More concentrated = more negative water potential!

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Plant cells have two components affecting water movement: solute potential (Ψs) relates to solute concentration only, whilst pressure potential (Ψp) is the effect of pressure on the solution. The formula is: Ψcell = Ψs + Ψp.
In hypotonic solutions, plant cell vacuoles increase in size, pushing the cell membrane against the cell wall and creating turgor pressure. This turgidity gives plants structural support - it's why plants wilt when they lack water.
Pressure potential should be positive and varies from 0 in fully plasmolysed cells to maximum in turgid cells.
Plant Support: Turgor pressure is what keeps plants standing upright!

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In hypertonic solutions, plant cell vacuoles shrink, pulling the cell membrane away from the wall - this process is called plasmolysis. The cell loses its structural support and becomes floppy.
Isotonic solutions create equilibrium with equal amounts of water entering and leaving the cell. This state is called incipient plasmolysis, where the membrane begins to lose contact with the cell wall.
You can observe three distinct states: plasmolysed (shrunken), flaccid (limp), and turgid (firm and upright).
Plant Health Check: Turgid = healthy, plasmolysed = dehydrated!

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Animal cells face greater osmotic challenges because they lack protective cell walls. In hypotonic solutions, water enters animal cells, and if too much gets in, the cells burst - this destructive process is called cell lysis.
In hypertonic solutions, water leaves animal cells, causing them to shrink and shrivel up. This is why maintaining proper fluid balance is crucial for animal survival.
Unlike plant cells that can benefit from some water pressure, animal cells need to maintain careful water balance to avoid damage.
No Protection: Without cell walls, animal cells are more vulnerable to osmotic damage!
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user