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03/12/2025
Biology
Biology B13 - Reproduction
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3 Dec 2025
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Understanding Biology B13: Reproduction - AQA GCSE Guide
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Imogen
@imogenxo
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Types of Reproduction
Ever wondered why you look like a mix of both your parents rather than an exact copy? That's because humans reproduce sexually, which creates genetic variation in offspring.
Sexual reproduction involves two parents and requires gametes (sex cells like sperm and eggs) to fuse together. These gametes are produced through meiosis, which halves the chromosome number and mixes genetic information. This mixing creates variation, meaning no two offspring are identical.
Asexual reproduction only needs one parent and produces clones - genetically identical offspring. Organisms like bacteria use mitosis to divide, creating exact copies of themselves. Whilst this is faster and requires less energy, it means all offspring have identical genes.
Quick Tip: Remember "A" for asexual = "A"ll the same (clones), whilst sexual reproduction creates variety!
The key trade-off? Sexual reproduction takes more time and energy but creates variation that helps species survive environmental changes. Asexual reproduction is efficient but risky if conditions change, since all offspring are identical.
Cell Division and Fertilisation
Meiosis is the special type of cell division that happens in your sex organs (gonads) to produce gametes. Unlike regular cell division, meiosis creates four cells with half the normal chromosome number - that's why it's called "reduction division."
The process works in stages: first, DNA replicates and chromosomes pair up. Then the nucleus divides twice, separating chromosomes randomly into four unique gametes. In humans, this means each gamete gets 23 chromosomes instead of the usual 46.
Fertilisation restores the full chromosome number when two gametes join. A human sperm (23 chromosomes) plus an egg (23 chromosomes) creates a zygote with 46 chromosomes. This combination is completely unique - even your siblings have different genetic combinations!
Remember: Meiosis makes gametes with half the chromosomes, fertilisation puts them back together!
Different organisms reproduce in fascinating ways. Fungi release spores when conditions are good, but switch to sexual reproduction when stressed. Plants can reproduce through flowers (sexual) or runners (asexual). Even malaria parasites change their reproduction method depending on whether they're in humans or mosquitoes.
DNA Structure and Protein Synthesis
DNA (deoxyribonucleic acid) is like your body's instruction manual, stored in every cell nucleus as a twisted double helix structure. This polymer contains genes - sections of DNA that code for specific proteins your body needs to function.
The structure is surprisingly simple: alternating sugar and phosphate sections form the backbone, with bases (A, T, C, G) attached to each sugar. These bases always pair specifically - A with T, and C with G. Each group of three bases codes for one amino acid, the building blocks of proteins.
Protein synthesis happens when your cells need to make specific proteins. First, a template of the DNA code is made and travels to a ribosome. Then, carrier molecules bring amino acids in the correct order, linking them together to form a protein that folds into its functional shape.
Key Point: Changes in just three DNA bases can alter an entire protein - that's how powerful genes are!
The human genome contains over 21,000 genes across billions of base pairs. Scientists mapped this through the Human Genome Project (1990-2003), helping us understand genetic diseases and relationships between species. Gene expression determines which proteins get made when, whilst mutations - random changes in DNA - can alter protein function for better or worse.
Genetic Inheritance and Disorders
Understanding genetic terminology helps you predict inheritance patterns. Your genotype refers to the actual alleles you carry (like Bb), whilst your phenotype is what you actually look like (brown eyes). Dominant alleles always show up in your phenotype, even with just one copy.
Polydactyly (extra fingers or toes) is caused by a dominant allele, meaning you only need to inherit it from one parent to have the condition. Surgery can remove extra digits, making this a manageable disorder.
Cystic fibrosis works differently - it's recessive, so you need two copies (one from each parent) to have the condition. CF causes thick mucus that blocks airways and digestive tubes, leading to breathing problems and weight loss. Treatment includes physiotherapy, antibiotics, and digestive enzymes.
Memory Tip: Dominant alleles are "bossy" - they always show up. Recessive alleles are "shy" - they need a partner to appear!
Genetic screening can detect these conditions early through amniocentesis or chorionic villus sampling . Whilst screening prevents serious health problems, it raises ethical questions about "designer babies" and increases miscarriage risk. Currently, it's mainly offered to families with genetic disorder histories or older parents.
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This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
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The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
Understanding Biology B13: Reproduction - AQA GCSE Guide
I
Imogen
@imogenxo
Sexual and asexual reproduction are the two main ways organisms create offspring, each with distinct advantages and disadvantages. Understanding how DNA, genes, and chromosomes work together helps explain inheritance patterns and genetic disorders you might encounter in biology.
Types of Reproduction
Ever wondered why you look like a mix of both your parents rather than an exact copy? That's because humans reproduce sexually, which creates genetic variation in offspring.
Sexual reproduction involves two parents and requires gametes (sex cells like sperm and eggs) to fuse together. These gametes are produced through meiosis, which halves the chromosome number and mixes genetic information. This mixing creates variation, meaning no two offspring are identical.
Asexual reproduction only needs one parent and produces clones - genetically identical offspring. Organisms like bacteria use mitosis to divide, creating exact copies of themselves. Whilst this is faster and requires less energy, it means all offspring have identical genes.
Quick Tip: Remember "A" for asexual = "A"ll the same (clones), whilst sexual reproduction creates variety!
The key trade-off? Sexual reproduction takes more time and energy but creates variation that helps species survive environmental changes. Asexual reproduction is efficient but risky if conditions change, since all offspring are identical.
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Cell Division and Fertilisation
Meiosis is the special type of cell division that happens in your sex organs (gonads) to produce gametes. Unlike regular cell division, meiosis creates four cells with half the normal chromosome number - that's why it's called "reduction division."
The process works in stages: first, DNA replicates and chromosomes pair up. Then the nucleus divides twice, separating chromosomes randomly into four unique gametes. In humans, this means each gamete gets 23 chromosomes instead of the usual 46.
Fertilisation restores the full chromosome number when two gametes join. A human sperm (23 chromosomes) plus an egg (23 chromosomes) creates a zygote with 46 chromosomes. This combination is completely unique - even your siblings have different genetic combinations!
Remember: Meiosis makes gametes with half the chromosomes, fertilisation puts them back together!
Different organisms reproduce in fascinating ways. Fungi release spores when conditions are good, but switch to sexual reproduction when stressed. Plants can reproduce through flowers (sexual) or runners (asexual). Even malaria parasites change their reproduction method depending on whether they're in humans or mosquitoes.
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DNA Structure and Protein Synthesis
DNA (deoxyribonucleic acid) is like your body's instruction manual, stored in every cell nucleus as a twisted double helix structure. This polymer contains genes - sections of DNA that code for specific proteins your body needs to function.
The structure is surprisingly simple: alternating sugar and phosphate sections form the backbone, with bases (A, T, C, G) attached to each sugar. These bases always pair specifically - A with T, and C with G. Each group of three bases codes for one amino acid, the building blocks of proteins.
Protein synthesis happens when your cells need to make specific proteins. First, a template of the DNA code is made and travels to a ribosome. Then, carrier molecules bring amino acids in the correct order, linking them together to form a protein that folds into its functional shape.
Key Point: Changes in just three DNA bases can alter an entire protein - that's how powerful genes are!
The human genome contains over 21,000 genes across billions of base pairs. Scientists mapped this through the Human Genome Project (1990-2003), helping us understand genetic diseases and relationships between species. Gene expression determines which proteins get made when, whilst mutations - random changes in DNA - can alter protein function for better or worse.
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Genetic Inheritance and Disorders
Understanding genetic terminology helps you predict inheritance patterns. Your genotype refers to the actual alleles you carry (like Bb), whilst your phenotype is what you actually look like (brown eyes). Dominant alleles always show up in your phenotype, even with just one copy.
Polydactyly (extra fingers or toes) is caused by a dominant allele, meaning you only need to inherit it from one parent to have the condition. Surgery can remove extra digits, making this a manageable disorder.
Cystic fibrosis works differently - it's recessive, so you need two copies (one from each parent) to have the condition. CF causes thick mucus that blocks airways and digestive tubes, leading to breathing problems and weight loss. Treatment includes physiotherapy, antibiotics, and digestive enzymes.
Memory Tip: Dominant alleles are "bossy" - they always show up. Recessive alleles are "shy" - they need a partner to appear!
Genetic screening can detect these conditions early through amniocentesis or chorionic villus sampling . Whilst screening prevents serious health problems, it raises ethical questions about "designer babies" and increases miscarriage risk. Currently, it's mainly offered to families with genetic disorder histories or older parents.
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The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
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Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
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The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user