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PsychologyPsychology324 views·Updated May 24, 2026·2 pages

Understanding Synaptic Transmission: Structure and Function

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Demetra@demetra_21

Your brain processes information through electrical and chemical signals that... Show more

1
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# Synaptic Transmission

ACTION POTENTIAL

• At resting state, the inside of a cell is negatively charged relative to the outside.
• When a

Action Potential and Neural Firing

Think of neurons like tiny electrical switches that can flip from "off" to "on" in milliseconds. At rest, the inside of a neuron is negatively charged compared to the outside, but when stimulated, it rapidly flips to become positively charged through a process called depolarisation.

This electrical flip creates an action potential - basically an electrical impulse that races down the neuron's axon like electricity through a wire. The brilliant thing is that this only happens when the stimulus reaches a specific threshold - it's an all-or-nothing response that fires at the same intensity every time.

If the threshold isn't reached, nothing happens at all. Once it does fire, the neuron quickly returns to its resting state through repolarisation, ready to fire again when needed.

Key Point: The action potential is like a light switch - it's either completely on or completely off, never halfway!

2
of 2
# Synaptic Transmission

ACTION POTENTIAL

• At resting state, the inside of a cell is negatively charged relative to the outside.
• When a

Synaptic Transmission and Chemical Messengers

When that electrical impulse reaches the end of a neuron, something amazing happens - it triggers the release of chemical messengers called neurotransmitters. These chemicals are stored in tiny sacs called vesicles that dump their contents into the gap between neurons (the synaptic cleft) through a process called exocytosis.

The neurotransmitters then drift across this microscopic gap and bind to specific receptors on the next neuron, like keys fitting into locks. Depending on which neurotransmitter it is, this binding can either make the next neuron more likely to fire (excitatory) or less likely (inhibitory).

After doing their job, neurotransmitters are either broken down by enzymes or recycled back into the original neuron through reuptake. Key players include GABA (your brain's brake pedal for anxiety), dopamine (linked to pleasure and addiction), glutamate (essential for learning), and serotonin (your mood booster that also controls sleep).

Remember: Each neurotransmitter has its own specific job - like having different tools for different tasks in your brain's toolkit!

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PsychologyPsychology324 views·Updated May 24, 2026·2 pages

Understanding Synaptic Transmission: Structure and Function

user profile picture
Demetra@demetra_21

Your brain processes information through electrical and chemical signals that jump between neurons. Understanding how synaptic transmission works is crucial for grasping how everything from your thoughts to your emotions actually happen at a biological level.

1
of 2
# Synaptic Transmission

ACTION POTENTIAL

• At resting state, the inside of a cell is negatively charged relative to the outside.
• When a

Sign up to see the content. It's free!

  • Access to all documents
  • Improve your grades
  • Join milions of students

Action Potential and Neural Firing

Think of neurons like tiny electrical switches that can flip from "off" to "on" in milliseconds. At rest, the inside of a neuron is negatively charged compared to the outside, but when stimulated, it rapidly flips to become positively charged through a process called depolarisation.

This electrical flip creates an action potential - basically an electrical impulse that races down the neuron's axon like electricity through a wire. The brilliant thing is that this only happens when the stimulus reaches a specific threshold - it's an all-or-nothing response that fires at the same intensity every time.

If the threshold isn't reached, nothing happens at all. Once it does fire, the neuron quickly returns to its resting state through repolarisation, ready to fire again when needed.

Key Point: The action potential is like a light switch - it's either completely on or completely off, never halfway!

2
of 2
# Synaptic Transmission

ACTION POTENTIAL

• At resting state, the inside of a cell is negatively charged relative to the outside.
• When a

Sign up to see the content. It's free!

  • Access to all documents
  • Improve your grades
  • Join milions of students

Synaptic Transmission and Chemical Messengers

When that electrical impulse reaches the end of a neuron, something amazing happens - it triggers the release of chemical messengers called neurotransmitters. These chemicals are stored in tiny sacs called vesicles that dump their contents into the gap between neurons (the synaptic cleft) through a process called exocytosis.

The neurotransmitters then drift across this microscopic gap and bind to specific receptors on the next neuron, like keys fitting into locks. Depending on which neurotransmitter it is, this binding can either make the next neuron more likely to fire (excitatory) or less likely (inhibitory).

After doing their job, neurotransmitters are either broken down by enzymes or recycled back into the original neuron through reuptake. Key players include GABA (your brain's brake pedal for anxiety), dopamine (linked to pleasure and addiction), glutamate (essential for learning), and serotonin (your mood booster that also controls sleep).

Remember: Each neurotransmitter has its own specific job - like having different tools for different tasks in your brain's toolkit!

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

Can't find what you're looking for? Explore other subjects.

Students love us — and so will you.

4.6/5App Store
4.7/5Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan SiOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha KlichAndroid user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

AnnaiOS user