Subjects
Maths
Chemistry
Biology
English Language
History
Responding to change (a2 only)
Infection and response
Homeostasis and response
Energy transfers (a2 only)
Cell biology
Organisms respond to changes in their internal and external environments (a-level only)
Biological molecules
Organisation
Substance exchange
Bioenergetics
Genetic information & variation
Inheritance, variation and evolution
Genetics & ecosystems (a2 only)
Ecology
Cells
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Britain & the wider world: 1745 -1901
1l the quest for political stability: germany, 1871-1991
The cold war
Inter-war germany
Medieval period: 1066 -1509
2d religious conflict and the church in england, c1529-c1570
2o democracy and nazism: germany, 1918-1945
1f industrialisation and the people: britain, c1783-1885
1c the tudors: england, 1485-1603
2m wars and welfare: britain in transition, 1906-1957
World war two & the holocaust
2n revolution and dictatorship: russia, 1917-1953
2s the making of modern britain, 1951-2007
World war one
Britain: 1509 -1745
Show all topics
Biology
16 Dec 2025
67
4 pages
Tumininu @tumininu
Your heart works non-stop to keep you alive, but sometimes things can go wrong with this vital organ.... Show more
Ever wondered what happens when your heart's "fuel lines" get clogged? Cardiovascular disease occurs when fatty deposits build up in your arteries, creating dangerous blockages that restrict blood flow.
Coronary heart disease is the most serious form of this condition. Your heart muscle needs a constant supply of oxygen through the coronary arteries, but when these vital blood vessels become blocked, your heart cells can't get the oxygen they need to function properly.
When a complete blockage occurs due to a blood clot, that section of heart muscle dies from lack of oxygen. This is what we call a heart attack, and it's a medical emergency that requires immediate treatment.
Remember Your arteries are like motorways for your blood - when they get blocked, everything backs up and problems start quickly.
When your heart's blood supply is compromised, doctors have several powerful tools to help restore normal function. Stents are tiny wire mesh tubes that act like scaffolding inside blocked arteries, widening them permanently to restore blood flow.
Heart bypass surgery takes a more dramatic approach by using a healthy artery from elsewhere in your body (often your leg) to create a new route around the blockage. Think of it like building a new road when the main one is blocked.
Statins work differently - they're medications that balance your cholesterol levels by increasing the "good" HDL cholesterol and reducing the "bad" LDL cholesterol. Unlike surgery, this is a daily medication that prevents future problems rather than fixing existing blockages.
Quick Comparison Stents are quick but risky, bypass surgery is major but effective, and statins are simple but lifelong.
Your heart has four crucial valves that work like one-way doors, ensuring blood flows in the right direction and doesn't leak backwards. When these valves become damaged, they either become too narrow (restricting flow) or too loose (allowing backflow).
Damaged valves need replacement surgery using either biological valves (from pig or cow tissue) or mechanical valves (made from metal and carbon). This major surgery requires stopping the heart temporarily whilst the replacement takes place.
The good news is that many risk factors for cardiovascular disease are completely under your control. High blood pressure, smoking, high cholesterol, an inactive lifestyle, and obesity all significantly increase your chances of developing heart problems.
Empowering Fact Most heart disease is preventable through lifestyle choices you make every single day.
When all other treatments fail, doctors have two final options heart transplants and artificial hearts. A heart transplant offers a permanent solution with significantly increased lifespan, but it comes with massive challenges including finding a suitable donor and lifelong immune-suppressing medications.
Artificial hearts provide immediate treatment without the risk of rejection, since your body won't attack the mechanical device. However, they're typically temporary solutions used whilst waiting for a real heart to become available.
Both options involve incredibly complex surgery with serious risks including infection, blood clots, and complications. The choice between them often depends on how urgently treatment is needed and whether a suitable donor heart is available.
Reality Check These treatments represent medical miracles that were impossible just decades ago - science continues to save lives in amazing ways.
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
6
Smart Tools NEW
Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines
Quotes from every main character
English LiteratureApp Store
Google Play
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
Tumininu
@tumininu
Your heart works non-stop to keep you alive, but sometimes things can go wrong with this vital organ. Understanding cardiovascular disease and its treatments is crucial knowledge that could literally be lifesaving for you or someone you care about.
Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Ever wondered what happens when your heart's "fuel lines" get clogged? Cardiovascular disease occurs when fatty deposits build up in your arteries, creating dangerous blockages that restrict blood flow.
Coronary heart disease is the most serious form of this condition. Your heart muscle needs a constant supply of oxygen through the coronary arteries, but when these vital blood vessels become blocked, your heart cells can't get the oxygen they need to function properly.
When a complete blockage occurs due to a blood clot, that section of heart muscle dies from lack of oxygen. This is what we call a heart attack, and it's a medical emergency that requires immediate treatment.
Remember: Your arteries are like motorways for your blood - when they get blocked, everything backs up and problems start quickly.
Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
When your heart's blood supply is compromised, doctors have several powerful tools to help restore normal function. Stents are tiny wire mesh tubes that act like scaffolding inside blocked arteries, widening them permanently to restore blood flow.
Heart bypass surgery takes a more dramatic approach by using a healthy artery from elsewhere in your body (often your leg) to create a new route around the blockage. Think of it like building a new road when the main one is blocked.
Statins work differently - they're medications that balance your cholesterol levels by increasing the "good" HDL cholesterol and reducing the "bad" LDL cholesterol. Unlike surgery, this is a daily medication that prevents future problems rather than fixing existing blockages.
Quick Comparison: Stents are quick but risky, bypass surgery is major but effective, and statins are simple but lifelong.
Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Your heart has four crucial valves that work like one-way doors, ensuring blood flows in the right direction and doesn't leak backwards. When these valves become damaged, they either become too narrow (restricting flow) or too loose (allowing backflow).
Damaged valves need replacement surgery using either biological valves (from pig or cow tissue) or mechanical valves (made from metal and carbon). This major surgery requires stopping the heart temporarily whilst the replacement takes place.
The good news is that many risk factors for cardiovascular disease are completely under your control. High blood pressure, smoking, high cholesterol, an inactive lifestyle, and obesity all significantly increase your chances of developing heart problems.
Empowering Fact: Most heart disease is preventable through lifestyle choices you make every single day.
Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
When all other treatments fail, doctors have two final options: heart transplants and artificial hearts. A heart transplant offers a permanent solution with significantly increased lifespan, but it comes with massive challenges including finding a suitable donor and lifelong immune-suppressing medications.
Artificial hearts provide immediate treatment without the risk of rejection, since your body won't attack the mechanical device. However, they're typically temporary solutions used whilst waiting for a real heart to become available.
Both options involve incredibly complex surgery with serious risks including infection, blood clots, and complications. The choice between them often depends on how urgently treatment is needed and whether a suitable donor heart is available.
Reality Check: These treatments represent medical miracles that were impossible just decades ago - science continues to save lives in amazing ways.
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
6
Smart Tools NEW
Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines
Quotes from every main character
English LiteratureApp Store
Google Play
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
Sociology