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AQA Biology Paper 2: Genetic Engineering & Hormonal Coordination for GCSE

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Olive Stevens

04/10/2025

Biology

Biology paper 2 aqa

4,941

4 Oct 2025

10 pages

AQA Biology Paper 2: Genetic Engineering & Hormonal Coordination for GCSE

user profile picture

Olive Stevens

@olivestevens_ssuw

Genetic Engineering and Metabolism in Biology: Key Concepts for GCSE... Show more

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Metabolism and Variation

Metabolism refers to all the chemical reactions that occur within living organisms. It includes both anabolic (building up) and catabolic (breaking down) processes.

Key metabolic processes:

  • Carbohydrate synthesis and breakdown
  • Protein synthesis and amino acid production
  • Lipid synthesis

Definition: Metabolism is the sum of all biochemical reactions in an organism.

Variation describes differences in characteristics between individuals in a population. Sources of variation include:

  • Genetic differences (inherited traits)
  • Environmental factors
  • Combinations of genes and environment

Highlight: Mutations are changes in DNA sequences that can lead to new traits, driving evolution when beneficial.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Genetic Inheritance and DNA

Meiosis is a type of cell division that produces gametes (sex cells) with half the normal number of chromosomes. Key points:

  • DNA replicates before cell division
  • Results in four genetically different daughter cells
  • Restores full chromosome number during fertilization

Vocabulary:

  • Gamete: Specialized sex cell formed by meiosis
  • Chromosome: Structure made of DNA found in cell nuclei
  • Allele: Different form of the same gene

DNA (deoxyribonucleic acid) is the genetic material found in cell nuclei. It has a double helix structure composed of two strands.

Key genetic concepts:

  • Genes are sections of DNA coding for specific proteins
  • The genome is an organism's complete set of genetic material
  • Genotype is the genetic makeup, while phenotype is the observable traits

Definition: A gene is a section of DNA that codes for a specific protein.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Sexual Reproduction and Selective Breeding

Sexual reproduction involves:

  • Two parents contributing genetic material
  • Production of gametes through meiosis
  • Fusion of male and female gametes (fertilization)

In animals, sperm fertilizes an egg. In plants, pollen fertilizes an ovule.

Selective breeding is the process of choosing organisms with desired traits to produce offspring.

Benefits:

  • Disease-resistant crops
  • Increased meat/milk production in livestock
  • Desired traits in domesticated animals

Example: Dogs have been selectively bred for traits like gentleness and specific physical characteristics.

Risks:

  • Reduced genetic diversity
  • Increased susceptibility to diseases
  • Inherited defects due to inbreeding

Highlight: While selective breeding can produce desired traits, it can also lead to health issues in some breeds due to limited genetic diversity.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Genetic Engineering and Cloning

Genetic engineering is the process of modifying an organism's genome by inserting genes from another organism. This allows the creation of organisms with desired traits.

Key steps in genetic engineering:

  1. Isolate desired gene
  2. Insert gene into a vector
  3. Transfer vector into target cell
  4. Allow modified organism to develop

Highlight: Genetic engineering has potential benefits like curing inherited diseases and improving crop yields, but also carries risks like gene transfer to wild species.

Cloning produces genetically identical organisms through asexual reproduction methods. Common cloning techniques include:

  • Tissue culture for plants
  • Embryo transplants for animals
  • Adult cell nuclear transfer (e.g. Dolly the sheep)

Example: Tissue culture involves growing new plants from small groups of plant cells, which is useful for preserving rare species.

Vocabulary: A clone is an organism that is genetically identical to its parent.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required
Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required
Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required
Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required
Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required
Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required


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This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

 

Biology

4,941

4 Oct 2025

10 pages

AQA Biology Paper 2: Genetic Engineering & Hormonal Coordination for GCSE

user profile picture

Olive Stevens

@olivestevens_ssuw

Genetic Engineering and Metabolism in Biology: Key Concepts for GCSE

This document covers essential topics in genetic engineering GCSE Biology and metabolism, including:

  • Genetic engineering techniques and applications
  • Cloning methods and their implications
  • Metabolism and key metabolic processes
  • Variation in... Show more

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Metabolism and Variation

Metabolism refers to all the chemical reactions that occur within living organisms. It includes both anabolic (building up) and catabolic (breaking down) processes.

Key metabolic processes:

  • Carbohydrate synthesis and breakdown
  • Protein synthesis and amino acid production
  • Lipid synthesis

Definition: Metabolism is the sum of all biochemical reactions in an organism.

Variation describes differences in characteristics between individuals in a population. Sources of variation include:

  • Genetic differences (inherited traits)
  • Environmental factors
  • Combinations of genes and environment

Highlight: Mutations are changes in DNA sequences that can lead to new traits, driving evolution when beneficial.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Genetic Inheritance and DNA

Meiosis is a type of cell division that produces gametes (sex cells) with half the normal number of chromosomes. Key points:

  • DNA replicates before cell division
  • Results in four genetically different daughter cells
  • Restores full chromosome number during fertilization

Vocabulary:

  • Gamete: Specialized sex cell formed by meiosis
  • Chromosome: Structure made of DNA found in cell nuclei
  • Allele: Different form of the same gene

DNA (deoxyribonucleic acid) is the genetic material found in cell nuclei. It has a double helix structure composed of two strands.

Key genetic concepts:

  • Genes are sections of DNA coding for specific proteins
  • The genome is an organism's complete set of genetic material
  • Genotype is the genetic makeup, while phenotype is the observable traits

Definition: A gene is a section of DNA that codes for a specific protein.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Sign up to see the contentIt's free!

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Sexual Reproduction and Selective Breeding

Sexual reproduction involves:

  • Two parents contributing genetic material
  • Production of gametes through meiosis
  • Fusion of male and female gametes (fertilization)

In animals, sperm fertilizes an egg. In plants, pollen fertilizes an ovule.

Selective breeding is the process of choosing organisms with desired traits to produce offspring.

Benefits:

  • Disease-resistant crops
  • Increased meat/milk production in livestock
  • Desired traits in domesticated animals

Example: Dogs have been selectively bred for traits like gentleness and specific physical characteristics.

Risks:

  • Reduced genetic diversity
  • Increased susceptibility to diseases
  • Inherited defects due to inbreeding

Highlight: While selective breeding can produce desired traits, it can also lead to health issues in some breeds due to limited genetic diversity.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

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Genetic Engineering and Cloning

Genetic engineering is the process of modifying an organism's genome by inserting genes from another organism. This allows the creation of organisms with desired traits.

Key steps in genetic engineering:

  1. Isolate desired gene
  2. Insert gene into a vector
  3. Transfer vector into target cell
  4. Allow modified organism to develop

Highlight: Genetic engineering has potential benefits like curing inherited diseases and improving crop yields, but also carries risks like gene transfer to wild species.

Cloning produces genetically identical organisms through asexual reproduction methods. Common cloning techniques include:

  • Tissue culture for plants
  • Embryo transplants for animals
  • Adult cell nuclear transfer (e.g. Dolly the sheep)

Example: Tissue culture involves growing new plants from small groups of plant cells, which is useful for preserving rare species.

Vocabulary: A clone is an organism that is genetically identical to its parent.

Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Sign up to see the contentIt's free!

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

Sign up to see the contentIt's free!

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Genetic engineering
cell from
oorganism
with desired
gene
O
desired gene
cell with
vector
Jariation
vector used to insert gene
into required

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Improve your grades

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We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

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4.9/5

App Store

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Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user