Proteins: Structure and Function
Proteins are incredibly versatile molecules made from amino acids. Each amino acid contains an amino group, a carboxyl group, and a variable R group that determines its properties.
Amino acids join through condensation reactions, forming peptide bonds and releasing water. Two amino acids create a dipeptide, whilst long chains form polypeptides and proteins.
Protein structure has four levels. Primary structure is the amino acid sequence. Secondary structure involves folding into alpha helixes or beta sheets using hydrogen bonds. Tertiary structure creates 3D shapes through various bonds (hydrogen, ionic, disulphide). Quaternary structure combines multiple polypeptide chains.
Fibrous proteins like collagen, keratin, and elastin provide structural support. Collagen gives strength to tendons and bones. Keratin (rich in disulphide bridges) forms hair and nails. Elastin stretches in skin and blood vessels.
Globular proteins are spherical and water-soluble. Insulin regulates blood glucose levels, whilst pepsin digests proteins in your stomach. Their specific 3D shapes determine their functions.
Study Strategy: Focus on how structure determines function - a protein's shape directly relates to its job in the body.