Biological explanations of OCD encompass genetic and neural factors that contribute to the disorder's development, including specific gene variations and brain structure abnormalities.
Key points:
- The COMT and SERT genes play crucial roles in neurotransmitter regulation
- Brain regions like the basal ganglia and orbitofrontal cortex show altered activity
- Twin studies provide strong evidence for genetic influence
- Treatment applications include SSRI medications
- Limitations include correlation vs causation issues and nomothetic approach concerns