The Great Plague (1665): Same Disease, Same Failed Remedies
You'd think 300 years of medical progress would help with another plague outbreak - you'd be wrong! The Great Plague of 1665 killed thousands in London, and people's explanations were barely different from medieval times.
Causes blamed included unusual alignment of Saturn and Jupiter, God's punishment for sin, and miasma from rubbish and dung hills. At least people now understood it spread person-to-person, leading to proper quarantine measures.
Treatments were still useless: sweating the disease out, transference (strapping live chickens to infected buboes), and herbal remedies. Quack doctors with no qualifications took advantage of panic to sell fake cures, while plague doctors wore creepy beaked masks filled with sweet-smelling herbs.
Government action was more organised this time. King Charles II banned public meetings and funerals, lit fires on street corners to "drive away miasma," and killed 40,000 dogs plus 200,000 cats (thinking they spread disease). Wardens monitored households and enforced 40-day quarantines.
Bizarre Belief: Some people deliberately caught syphilis, thinking it would prevent plague because both diseases caused similar symptoms!