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Cell biology
Biological molecules
Organisation
Infection and response
Energy transfers (a2 only)
Homeostasis and response
Responding to change (a2 only)
The control of gene expression (a-level only)
Substance exchange
Bioenergetics
Genetic information & variation
Inheritance, variation and evolution
Genetics & ecosystems (a2 only)
Ecology
Cells
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1c the tudors: england, 1485-1603
1l the quest for political stability: germany, 1871-1991
Inter-war germany
1f industrialisation and the people: britain, c1783-1885
Britain & the wider world: 1745 -1901
2n revolution and dictatorship: russia, 1917-1953
2j america: a nation divided, c1845-1877
The cold war
World war two & the holocaust
World war one
Medieval period: 1066 -1509
The fight for female suffrage
2m wars and welfare: britain in transition, 1906-1957
2d religious conflict and the church in england, c1529-c1570
Britain: 1509 -1745
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11/05/2023
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P TOPIC 6. - where is it? DNA ① + AXT/GX C Adenine ~ Thyrine Guamine cyracine INHERITANCE, VARIATION & EVOLUTION - Structure. + made of repeating units called nucleotides ~ S chrome some gene sugars } bases J ~ phosphates complementary bases. DNA backbone + order of bases decide which amino acid makes proteins gines + small sections of ONA that codes for a specific protein + gename is genetic material of on ergorusm MRNA + proteins are made in ribesen + DNA in nucleus out needs to get toribosomes but too big * MRNA copies DNA code and acts as a messenger + Transcription - in nucleus -gent for protein code twists and unzips -free bases form complementary base pairs with one strand weak hydragen beney formLITE - A Gene MANA synthesises mRNA MANA peeks off and meves into cytoplasm to find ribesome. f Unzips bremes leaves nucleus - WHH complementary hydrogen bonds me finds ribosome + 。 · Translation - fines ribesome and attaches. ERNA transports specific amino acids to Tribesome. mRNA and tRNA match up peptide bonds form to create protein. chain 1 MIRNA finds ribosome D BINOS! HO pairs up with Complimentary base - ERNA PRO. releases protein B mutations + change sequence of DNA bases. insertions deletions - substitutions. Reproductions + sexual -twe parents -gametes + asexual B brings together protein A created ба sexual is better as it creates genent variation 2 - one parent - miteris XXxx xx xx clenca (ne variation) x X X x x Punnett squares X Y X XX XY X XX XY + • genetically different! "( # + >[ - 50% gin - 50%. bay Innented diseases. cystic fibrosis UC ☺ } recessive andle (both recessive needed) - mucus in air passages and pancreas. + polydactyly dominant avele (one necald) extra fingers or toes. D Vanation + genes cause genetic variation + characteristics can be influenced by the environment + mutations introduce variation Evolution + survival of the filtest -pass on charactenstics onto offspring +...
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phenotypes - contrated by genes and mutations the beneficial variations + speciation when phenotype changes so much, now species comes out + extinction + environment changes new predata hills off new disease ning them off - can't compete for food catastrophic event - - why did no-one agree with Darwin?. + against religions beliefs. + he could explain why or now as technology hadn't been developed to improve it + no enough evidence Comarch giraffe man if characteristic is used a let it will be passed on 101 • 102 selective Breeding. + humans select best characteristics and breed for better + examples - mere meat / mich disease resistance. - geed temprament. big flowers_0 + reduces gene pad f inbreeding leads to health problems. - if disease cernes aleng etc. (all dead) IDA ALIQU M Genetic Engineering. transferring desired gene into another organim fo 773 + uses. - O C O genetically produced insulin genetically modifyed crops. gene therapy PPP a * controversies! • not everyone agrees. Long term effects unknown. 1- implanned problems. + GM crops - D Crips can help in poverteus countries as golden rice gives numents that can stop blindness ·ne problems. so far. Cloning + plants - tissue culture. -Cons effect number of wildflowers and umit biodiversity ♥ safety? · genes escape accidentally creating super- weeds + animals plant cells put in growth meaison with hermenes and are clones of parent - cuttings ~ aittings taken from parent plant and are grann embryo transplants ~cag and sperm artificially fertilized emoryo cells split and bust in different methers. 104 + adult cell cloning • Donly the sheep -unfertilised egg with remered nucleus nucleus from adult cell interce in it's place - implanted in wemb + issues reduses gene pool -age related awarders could nep endangered 25 - net as healthy. Fossils + remains of plants and animals + formation gradual replacement by minerals. ~ hard things like teethana bines don't decay easily, eventually replaced by minerus and forms TOCK like Jubstance. cars and impressions. when buried in reft material winte clay, hardens and body decays ~ - preservation in order and far pits there is no aygen to delay microbes don't jurive, also in glaciers as the cold and in peat nogs as too desdic 。 D speciation + development of new species. & Alfred Russel wanace classification. DAL + Woese - archaea * - bacteria ankarjeta Family Antibiotic Resistant Bacteria * bacteria can evoive due to randam mutations + due to quick reproduction it's an issue + MASA superbug and is fatal! + mere commen due to incorrect usage. kinadem A MA Cian M Phylum CO₂ order AA ● Genus species Linnean system - Binsmial rystem (named by genus & species) 105