Synaptic transmission is the process by which neurons communicate with...
How Synaptic Transmission Works: Understanding Neurotransmitters

Synaptic Transmission Basics
Ever wondered how your brain cells talk to each other? Neurons communicate at junctions called synapses, where an electrical signal from one neuron gets transformed into a chemical message. This process is crucial for everything from your thoughts to movements!
When an electrical impulse reaches the end of a neuron (the presynaptic terminal), it triggers the release of chemicals called neurotransmitters from tiny sacs called synaptic vesicles. These neurotransmitters cross the gap (synaptic cleft) and attach to receptor sites on the receiving neuron, where they're converted back into electrical signals.
Different neurotransmitters have specific effects on our brain and body. For example, serotonin influences mood and social behaviour, with low levels being linked to depression. Neurotransmitters generally have either excitatory effects (making the next neuron more likely to fire, like adrenaline) or inhibitory effects (making it less likely to fire, like serotonin). Dopamine is unusual as it can be either excitatory or inhibitory.
Remember this! When excitatory signals outweigh inhibitory ones, a process called summation occurs, causing the neuron to fire an electrical impulse. This balance of excitation and inhibition is how your brain processes information!
We thought you’d never ask...
Similar content
Most popular content: Synapse
1Most popular content in Biology
9A-Level Biology Year 1 Overview
Comprehensive summary of AQA A-Level Biology Year 1, covering key topics such as cellular structure, protein synthesis, immune response, gas exchange, and more. Ideal for exam preparation and understanding biological concepts. Includes detailed insights into cellular processes, biological classification, and the circulatory system.
AQA Biology: Key Concepts
Explore essential AQA Biology topics including Photosynthesis, Respiration, Homeostasis, Genetics, and Ecology. This comprehensive knowledge organizer covers key concepts such as energy transfer, hormonal control, and genetic variation, providing a solid foundation for your studies. Ideal for exam preparation and understanding biological processes.
Biology P2: Evolution & Adaptation
Explore key concepts in AQA GCSE Biology P2, focusing on evolution, natural selection, genetic engineering, and adaptations in organisms. This summary covers essential topics such as DNA structure, speciation, and the impact of environmental changes on biodiversity. Ideal for exam preparation and understanding complex biological processes.
A-Level Biology Year 2 Overview
Comprehensive study notes covering key concepts in AQA A-Level Biology Year 2, including neuronal communication, genetic modification, nutrient cycles, and hormonal control. This resource is designed to aid understanding of complex topics such as action potentials, photosynthesis, and speciation. Ideal for exam preparation and revision.
biology paper 1
all notes
Biology Paper 1 Overview
Comprehensive study notes covering key concepts in cellular biology, human digestion, respiration, photosynthesis, and the circulatory system. This resource includes detailed explanations of cell structures, enzyme functions, nutrient absorption, and the impact of environmental factors on biological processes. Ideal for students preparing for Biology Paper 1 exams.
Biology paper 1 foundation & higher
Pages from the revision guide summarised in a set of words and a brief explanation
KS3 Biology
KS3 Biology revision document.
Paper 2 chemistry mindmaps
Condesnsed aqa triple higher
Most popular content
9Comprehensive Crime & Deviance Overview
Explore an extensive revision of crime and deviance topics, including theories, types of crime, and the impact of media. This resource covers key concepts such as Marxism, functionalism, gender and crime, and the influence of globalization on criminal behavior. Ideal for students seeking a thorough understanding of criminology and its various theories. Type: Full Topic Revision.
Sociological Theories Overview
Comprehensive revision of key sociological theories including Functionalism, Marxism, Feminism, and Interpretivism. Explore concepts like value freedom, identity formation, and the critique of social control. Ideal for AQA A-Level Sociology students preparing for exams. This summary covers essential theories and their implications in sociology, providing a clear understanding of each perspective.
Sociology of Families: Comprehensive Revision
Dive into an extensive overview of family dynamics, perspectives, and patterns in sociology. This resource covers key concepts such as family diversity, gender roles, marriage, and the impact of social policies on family structures. Perfect for A-Level Sociology students preparing for Paper 2.
Sociology of Education Overview
Explore comprehensive A-Level Sociology notes on the education system, covering key theories, policies, and sociological perspectives. This resource includes insights on marketisation, gender roles, cultural deprivation, and educational inequalities, providing a thorough understanding of how education shapes social stratification and individual achievement. Ideal for exam preparation and in-depth study.
Crime and Deviance AQA A-level sociology
AQA A-level crime and deviance topic notes
Chemistry paper 2
Chem paper 2 notes
A-Level Biology Year 1 Overview
Comprehensive summary of AQA A-Level Biology Year 1, covering key topics such as cellular structure, protein synthesis, immune response, gas exchange, and more. Ideal for exam preparation and understanding biological concepts. Includes detailed insights into cellular processes, biological classification, and the circulatory system.
AQA Biology: Key Concepts
Explore essential AQA Biology topics including Photosynthesis, Respiration, Homeostasis, Genetics, and Ecology. This comprehensive knowledge organizer covers key concepts such as energy transfer, hormonal control, and genetic variation, providing a solid foundation for your studies. Ideal for exam preparation and understanding biological processes.
Biology P2: Evolution & Adaptation
Explore key concepts in AQA GCSE Biology P2, focusing on evolution, natural selection, genetic engineering, and adaptations in organisms. This summary covers essential topics such as DNA structure, speciation, and the impact of environmental changes on biodiversity. Ideal for exam preparation and understanding complex biological processes.
Students love us — and so will you.
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
How Synaptic Transmission Works: Understanding Neurotransmitters
Synaptic transmission is the process by which neurons communicate with each other at junctions called synapses. While signals travel electrically within neurons, they must cross the gap between neurons chemically, using special messenger molecules called neurotransmitters.

Synaptic Transmission Basics
Ever wondered how your brain cells talk to each other? Neurons communicate at junctions called synapses, where an electrical signal from one neuron gets transformed into a chemical message. This process is crucial for everything from your thoughts to movements!
When an electrical impulse reaches the end of a neuron (the presynaptic terminal), it triggers the release of chemicals called neurotransmitters from tiny sacs called synaptic vesicles. These neurotransmitters cross the gap (synaptic cleft) and attach to receptor sites on the receiving neuron, where they're converted back into electrical signals.
Different neurotransmitters have specific effects on our brain and body. For example, serotonin influences mood and social behaviour, with low levels being linked to depression. Neurotransmitters generally have either excitatory effects (making the next neuron more likely to fire, like adrenaline) or inhibitory effects (making it less likely to fire, like serotonin). Dopamine is unusual as it can be either excitatory or inhibitory.
Remember this! When excitatory signals outweigh inhibitory ones, a process called summation occurs, causing the neuron to fire an electrical impulse. This balance of excitation and inhibition is how your brain processes information!
We thought you’d never ask...
Similar content
Most popular content: Synapse
1Most popular content in Biology
9A-Level Biology Year 1 Overview
Comprehensive summary of AQA A-Level Biology Year 1, covering key topics such as cellular structure, protein synthesis, immune response, gas exchange, and more. Ideal for exam preparation and understanding biological concepts. Includes detailed insights into cellular processes, biological classification, and the circulatory system.
AQA Biology: Key Concepts
Explore essential AQA Biology topics including Photosynthesis, Respiration, Homeostasis, Genetics, and Ecology. This comprehensive knowledge organizer covers key concepts such as energy transfer, hormonal control, and genetic variation, providing a solid foundation for your studies. Ideal for exam preparation and understanding biological processes.
Biology P2: Evolution & Adaptation
Explore key concepts in AQA GCSE Biology P2, focusing on evolution, natural selection, genetic engineering, and adaptations in organisms. This summary covers essential topics such as DNA structure, speciation, and the impact of environmental changes on biodiversity. Ideal for exam preparation and understanding complex biological processes.
A-Level Biology Year 2 Overview
Comprehensive study notes covering key concepts in AQA A-Level Biology Year 2, including neuronal communication, genetic modification, nutrient cycles, and hormonal control. This resource is designed to aid understanding of complex topics such as action potentials, photosynthesis, and speciation. Ideal for exam preparation and revision.
biology paper 1
all notes
Biology Paper 1 Overview
Comprehensive study notes covering key concepts in cellular biology, human digestion, respiration, photosynthesis, and the circulatory system. This resource includes detailed explanations of cell structures, enzyme functions, nutrient absorption, and the impact of environmental factors on biological processes. Ideal for students preparing for Biology Paper 1 exams.
Biology paper 1 foundation & higher
Pages from the revision guide summarised in a set of words and a brief explanation
KS3 Biology
KS3 Biology revision document.
Paper 2 chemistry mindmaps
Condesnsed aqa triple higher
Most popular content
9Comprehensive Crime & Deviance Overview
Explore an extensive revision of crime and deviance topics, including theories, types of crime, and the impact of media. This resource covers key concepts such as Marxism, functionalism, gender and crime, and the influence of globalization on criminal behavior. Ideal for students seeking a thorough understanding of criminology and its various theories. Type: Full Topic Revision.
Sociological Theories Overview
Comprehensive revision of key sociological theories including Functionalism, Marxism, Feminism, and Interpretivism. Explore concepts like value freedom, identity formation, and the critique of social control. Ideal for AQA A-Level Sociology students preparing for exams. This summary covers essential theories and their implications in sociology, providing a clear understanding of each perspective.
Sociology of Families: Comprehensive Revision
Dive into an extensive overview of family dynamics, perspectives, and patterns in sociology. This resource covers key concepts such as family diversity, gender roles, marriage, and the impact of social policies on family structures. Perfect for A-Level Sociology students preparing for Paper 2.
Sociology of Education Overview
Explore comprehensive A-Level Sociology notes on the education system, covering key theories, policies, and sociological perspectives. This resource includes insights on marketisation, gender roles, cultural deprivation, and educational inequalities, providing a thorough understanding of how education shapes social stratification and individual achievement. Ideal for exam preparation and in-depth study.
Crime and Deviance AQA A-level sociology
AQA A-level crime and deviance topic notes
Chemistry paper 2
Chem paper 2 notes
A-Level Biology Year 1 Overview
Comprehensive summary of AQA A-Level Biology Year 1, covering key topics such as cellular structure, protein synthesis, immune response, gas exchange, and more. Ideal for exam preparation and understanding biological concepts. Includes detailed insights into cellular processes, biological classification, and the circulatory system.
AQA Biology: Key Concepts
Explore essential AQA Biology topics including Photosynthesis, Respiration, Homeostasis, Genetics, and Ecology. This comprehensive knowledge organizer covers key concepts such as energy transfer, hormonal control, and genetic variation, providing a solid foundation for your studies. Ideal for exam preparation and understanding biological processes.
Biology P2: Evolution & Adaptation
Explore key concepts in AQA GCSE Biology P2, focusing on evolution, natural selection, genetic engineering, and adaptations in organisms. This summary covers essential topics such as DNA structure, speciation, and the impact of environmental changes on biodiversity. Ideal for exam preparation and understanding complex biological processes.
Students love us — and so will you.
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.