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9 Dec 2025

158

2 pages

How Synaptic Transmission Works: Understanding Neurotransmitters

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ℂ𝕒𝕣𝕣𝕠𝕥 @carrot74

Synaptic transmission is the process by which neurons communicate with each other at junctions called synapses. While signals... Show more

axon
synaptic vesicle
www
neurotransmitter
wwwww
presynaptic
nerve terminal
synaptic
cleft
dendrite
postsynaptic receptor sites # SYNAPTIC T

The Synapse Structure

The synapse is like a sophisticated relay station where messages pass from one neuron to another. At this junction, you'll find several specialized structures that make communication possible.

The presynaptic nerve terminal is where the action begins—it's the sending end of the synapse, packed with synaptic vesicles containing neurotransmitters ready to be released. When an electrical signal arrives down the axon (the neuron's main transmission line), these vesicles release their chemical messengers.

Between the sending and receiving neurons lies the synaptic cleft—a tiny gap that neurotransmitters must cross. On the other side, the receiving neuron has branched structures called dendrites dotted with postsynaptic receptor sites that catch the neurotransmitters like baseball gloves.

Did you know? The synaptic cleft is incredibly small—only about 20-40 nanometers wide! That's about 1/5000th the width of a human hair. Yet this tiny gap is where crucial brain communication happens.

axon
synaptic vesicle
www
neurotransmitter
wwwww
presynaptic
nerve terminal
synaptic
cleft
dendrite
postsynaptic receptor sites # SYNAPTIC T

Synaptic Transmission Basics

Ever wondered how your brain cells talk to each other? Neurons communicate at junctions called synapses, where an electrical signal from one neuron gets transformed into a chemical message. This process is crucial for everything from your thoughts to movements!

When an electrical impulse reaches the end of a neuron (the presynaptic terminal), it triggers the release of chemicals called neurotransmitters from tiny sacs called synaptic vesicles. These neurotransmitters cross the gap (synaptic cleft) and attach to receptor sites on the receiving neuron, where they're converted back into electrical signals.

Different neurotransmitters have specific effects on our brain and body. For example, serotonin influences mood and social behaviour, with low levels being linked to depression. Neurotransmitters generally have either excitatory effects (making the next neuron more likely to fire, like adrenaline) or inhibitory effects (making it less likely to fire, like serotonin). Dopamine is unusual as it can be either excitatory or inhibitory.

Remember this! When excitatory signals outweigh inhibitory ones, a process called summation occurs, causing the neuron to fire an electrical impulse. This balance of excitation and inhibition is how your brain processes information!

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This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

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Greenlight Bonnie

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very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

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I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

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THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

 

Biology

158

9 Dec 2025

2 pages

How Synaptic Transmission Works: Understanding Neurotransmitters

user profile picture

ℂ𝕒𝕣𝕣𝕠𝕥

@carrot74

Synaptic transmission is the process by which neurons communicate with each other at junctions called synapses. While signals travel electrically within neurons, they must cross the gap between neurons chemically, using special messenger molecules called neurotransmitters.

axon
synaptic vesicle
www
neurotransmitter
wwwww
presynaptic
nerve terminal
synaptic
cleft
dendrite
postsynaptic receptor sites # SYNAPTIC T

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The Synapse Structure

The synapse is like a sophisticated relay station where messages pass from one neuron to another. At this junction, you'll find several specialized structures that make communication possible.

The presynaptic nerve terminal is where the action begins—it's the sending end of the synapse, packed with synaptic vesicles containing neurotransmitters ready to be released. When an electrical signal arrives down the axon (the neuron's main transmission line), these vesicles release their chemical messengers.

Between the sending and receiving neurons lies the synaptic cleft—a tiny gap that neurotransmitters must cross. On the other side, the receiving neuron has branched structures called dendrites dotted with postsynaptic receptor sites that catch the neurotransmitters like baseball gloves.

Did you know? The synaptic cleft is incredibly small—only about 20-40 nanometers wide! That's about 1/5000th the width of a human hair. Yet this tiny gap is where crucial brain communication happens.

axon
synaptic vesicle
www
neurotransmitter
wwwww
presynaptic
nerve terminal
synaptic
cleft
dendrite
postsynaptic receptor sites # SYNAPTIC T

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Synaptic Transmission Basics

Ever wondered how your brain cells talk to each other? Neurons communicate at junctions called synapses, where an electrical signal from one neuron gets transformed into a chemical message. This process is crucial for everything from your thoughts to movements!

When an electrical impulse reaches the end of a neuron (the presynaptic terminal), it triggers the release of chemicals called neurotransmitters from tiny sacs called synaptic vesicles. These neurotransmitters cross the gap (synaptic cleft) and attach to receptor sites on the receiving neuron, where they're converted back into electrical signals.

Different neurotransmitters have specific effects on our brain and body. For example, serotonin influences mood and social behaviour, with low levels being linked to depression. Neurotransmitters generally have either excitatory effects (making the next neuron more likely to fire, like adrenaline) or inhibitory effects (making it less likely to fire, like serotonin). Dopamine is unusual as it can be either excitatory or inhibitory.

Remember this! When excitatory signals outweigh inhibitory ones, a process called summation occurs, causing the neuron to fire an electrical impulse. This balance of excitation and inhibition is how your brain processes information!

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

1

Smart Tools NEW

Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines

Mock Exam
Quiz
Flashcards
Essay

Most popular content in Biology

Most popular content

Can't find what you're looking for? Explore other subjects.

Students love us — and so will you.

4.9/5

App Store

4.8/5

Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user