Protein Synthesis: From DNA to Proteins
Think of a gene as a recipe book section - it's a specific part of a chromosome that contains the instructions for making one protein. Since proteins are built from amino acids, your DNA needs a clever coding system: every three base pairs (called a triplet codon) codes for exactly one amino acid.
The whole process happens in two main stages that work together like a perfectly coordinated team. Transcription occurs in the nucleus where the DNA recipe gets copied, whilst translation happens at ribosomes where the actual protein gets assembled.
Here's what makes this process brilliant: DNA can't leave the nucleus (it's too precious!), so cells use messenger RNA (mRNA) as a go-between. This single-stranded molecule can travel freely and carries the genetic code from nucleus to ribosome.
Transcription starts when RNA polymerase remember,enzymesendin′−ase′ latches onto the DNA and unzips it like a zipper. The mRNA then copies the DNA strand using complementary bases - but here's the twist: instead of thymine (T), RNA uses uracil (U).
During translation, the mRNA travels through nuclear pores to reach a ribosome. Transfer RNA (tRNA) molecules act like delivery trucks - each carries a specific amino acid and has a complementary codon that matches part of the mRNA sequence. As the ribosome moves along the mRNA, it joins the amino acids together to form the final protein, whilst the tRNA molecules head back to collect more amino acids.
Key Insight: The main difference between DNA and RNA is that DNA is double-stranded and stays in the nucleus with A, T, G, C bases, whilst RNA is single-stranded, can leave the nucleus, and uses A, U, G, C bases instead.