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9 Dec 2025

126

3 pages

Complete GCSE Biology AQA Topic 1 - Cells Study Guide

G

Georgia Greenslade @eorgiareenslade_cuhr

Living organisms are made up of cells that work in fascinating ways to keep life going. Understanding how... Show more

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Cell Structure and Types

All living things are made of cells, but not all cells are the same! Prokaryotes like bacteria are simple, single-celled organisms that are quite small. Eukaryotes include plants and animals - they're more complex and usually made of many cells working together.

Binary fission is how bacteria reproduce incredibly quickly. A single bacterium can divide every 30 minutes, so after just 2.5 hours, one cell becomes 32 cells! This rapid multiplication explains why bacterial infections can spread so fast.

Differentiation is the amazing process where cells become specialists. Stem cells start off with the potential to become any type of cell, then transform into specialised cells with specific jobs - like nerve cells or muscle cells.

Quick Tip Remember that stem cells are like blank canvases - they can become any type of cell your body needs!

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Cell Division and Specialised Cells

The cell cycle involves three main steps chromosomes replicate, they separate to opposite ends of the cell, then the cell splits into two identical daughter cells. Mitosis creates identical cells for growth and repair, whilst meiosis produces gametes (sex cells) for reproduction.

Your cells contain 23 pairs of chromosomes in the nucleus, which controls all cell activities. Different cell parts have specific jobs mitochondria provide energy, ribosomes make proteins, and in plant cells, chloroplasts carry out photosynthesis.

Specialised cells are perfectly designed for their jobs. Xylem cells transport water through hollow tubes strengthened with lignin. Phloem cells move sugars around plants using sieve plates. Root hair cells absorb water and minerals with lots of mitochondria for energy.

Nerve cells have long axons to carry electrical signals quickly, whilst muscle cells contain special proteins that slide over each other to create movement. Each cell type has evolved the perfect structure for its function.

Remember Every specialised cell started as a basic stem cell - differentiation is what makes them unique!

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Microscopes and Movement Across Membranes

Light microscopes use lenses to magnify specimens, whilst electron microscopes use electrons for much higher magnification and resolution. Light microscopes are cheaper and easier to use, but electron microscopes reveal incredible detail that's impossible to see otherwise.

Diffusion is the natural spreading of particles from high to low concentration - no energy required! Only small molecules like glucose can pass through cell membranes. Osmosis specifically describes water movement across partially permeable membranes.

Active transport works against the concentration gradient, moving substances from low to high concentration using energy from respiration. Root hair cells use this to absorb mineral ions from soil, even when there's more minerals inside the cell than outside.

Gas exchange surfaces like alveoli in lungs and gills in fish are perfectly adapted with large surface areas, thin walls for short diffusion distances, and excellent blood supplies to maintain concentration gradients.

Key Point Passive processes (diffusion, osmosis) need no energy, but active transport requires energy because it works against nature's flow!

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Stefan S

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This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

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Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

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Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

 

Biology

126

9 Dec 2025

3 pages

Complete GCSE Biology AQA Topic 1 - Cells Study Guide

G

Georgia Greenslade

@eorgiareenslade_cuhr

Living organisms are made up of cells that work in fascinating ways to keep life going. Understanding how cells are structured, how they divide, and how substances move in and out of them is essential for grasping the basics of... Show more

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Cell Structure and Types

All living things are made of cells, but not all cells are the same! Prokaryotes like bacteria are simple, single-celled organisms that are quite small. Eukaryotes include plants and animals - they're more complex and usually made of many cells working together.

Binary fission is how bacteria reproduce incredibly quickly. A single bacterium can divide every 30 minutes, so after just 2.5 hours, one cell becomes 32 cells! This rapid multiplication explains why bacterial infections can spread so fast.

Differentiation is the amazing process where cells become specialists. Stem cells start off with the potential to become any type of cell, then transform into specialised cells with specific jobs - like nerve cells or muscle cells.

Quick Tip: Remember that stem cells are like blank canvases - they can become any type of cell your body needs!

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Cell Division and Specialised Cells

The cell cycle involves three main steps: chromosomes replicate, they separate to opposite ends of the cell, then the cell splits into two identical daughter cells. Mitosis creates identical cells for growth and repair, whilst meiosis produces gametes (sex cells) for reproduction.

Your cells contain 23 pairs of chromosomes in the nucleus, which controls all cell activities. Different cell parts have specific jobs: mitochondria provide energy, ribosomes make proteins, and in plant cells, chloroplasts carry out photosynthesis.

Specialised cells are perfectly designed for their jobs. Xylem cells transport water through hollow tubes strengthened with lignin. Phloem cells move sugars around plants using sieve plates. Root hair cells absorb water and minerals with lots of mitochondria for energy.

Nerve cells have long axons to carry electrical signals quickly, whilst muscle cells contain special proteins that slide over each other to create movement. Each cell type has evolved the perfect structure for its function.

Remember: Every specialised cell started as a basic stem cell - differentiation is what makes them unique!

# Topic 1
# Biology

Organisms can be:

# Prokaryotes
- Simple and Smaller
(e.g. Bacteria)
- Single-celled organism

# Eukaryotes
- Complex

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Microscopes and Movement Across Membranes

Light microscopes use lenses to magnify specimens, whilst electron microscopes use electrons for much higher magnification and resolution. Light microscopes are cheaper and easier to use, but electron microscopes reveal incredible detail that's impossible to see otherwise.

Diffusion is the natural spreading of particles from high to low concentration - no energy required! Only small molecules like glucose can pass through cell membranes. Osmosis specifically describes water movement across partially permeable membranes.

Active transport works against the concentration gradient, moving substances from low to high concentration using energy from respiration. Root hair cells use this to absorb mineral ions from soil, even when there's more minerals inside the cell than outside.

Gas exchange surfaces like alveoli in lungs and gills in fish are perfectly adapted with large surface areas, thin walls for short diffusion distances, and excellent blood supplies to maintain concentration gradients.

Key Point: Passive processes (diffusion, osmosis) need no energy, but active transport requires energy because it works against nature's flow!

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

5

Smart Tools NEW

Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines

Mock Exam
Quiz
Flashcards
Essay

Most popular content: Biology

Most popular content in Biology

Most popular content

Can't find what you're looking for? Explore other subjects.

Students love us — and so will you.

4.9/5

App Store

4.8/5

Google Play

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.

Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user