Stage 2 - Citric Acid Cycle
The citric acid cycle, also known as the Krebs cycle, takes place in the matrix of the mitochondria. This stage is crucial for generating electron carriers and carbon dioxide as a waste product.
Key steps in the citric acid cycle:
- Acetyl group from acetyl coenzyme A combines with oxaloacetate to form citrate
- A series of enzyme-controlled reactions gradually convert citrate back to oxaloacetate
- Dehydrogenase enzymes remove hydrogen ions and high-energy electrons
- Hydrogen ions and electrons are passed to NAD+, forming NADH
- NADH transfers hydrogen ions and electrons to the electron transport chain
Definition: Citric acid cycle - A series of chemical reactions in cellular respiration that generates electron carriers and carbon dioxide from the breakdown of acetyl groups.
Highlight: The citric acid cycle is an aerobic process, occurring only in the presence of oxygen.
Vocabulary: Oxaloacetate - A four-carbon molecule that combines with the acetyl group to initiate the citric acid cycle.






