Biology1,463Updated 12 Sept 20265 pages

Comprehensive Biology Revision: Paper 1 Foundation & Higher

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Darcy Smyth@darcysmyth_aadg
B1-B4 Biology covers the fundamental concepts of how living things work, from the tiny cells that make up everything to the complex processes that keep organisms alive. You'll explore how substances move in and out of cells, how organs are specially designed for their jobs, and how plants make their own food whilst animals fight off diseases.
Biology paper 1 foundation & higher – page 1

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Cells and Transport

Every living thing is built from cells - think of them as biological building blocks with specific parts doing different jobs. Animal cells have a nucleus (containing genetic material), cytoplasm (full of enzymes), cell membrane (controlling what enters and exits), and mitochondria (powering the cell through respiration).

Plant cells have all these parts plus some extras: a cell wall for support, a vacuole filled with cell sap, and chloroplasts for photosynthesis. Some cells, like stem cells found in bone marrow, haven't specialised yet and can become any type of cell - that's why they're so useful in medicine.

Substances move around cells through different processes. Diffusion happens when particles spread from areas of high concentration to low concentration naturally. Osmosis is similar but specifically for water moving across membranes. Active transport is different - it moves molecules against the concentration gradient, which requires energy from the cell.

Quick Tip: Remember that plant cells have everything animal cells have, PLUS extra structures - never the other way around!

Biology paper 1 foundation & higher – page 2

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Organs and Enzymes

Your body's organs are perfectly designed for their jobs through specialised exchange surfaces. The lungs have tiny air sacs called alveoli with huge surface areas and thin walls for efficient gas exchange. Your small intestine has villi - finger-like projections that massively increase surface area for absorbing nutrients quickly.

Enzymes are biological catalysts that speed up reactions without being used up themselves. The main digestive enzymes you need to know are amylase (breaks down starch into sugars), protease (breaks down proteins into amino acids), and lipase (breaks down fats into glycerol and fatty acids).

Your heart pumps blood around your body through three types of blood vessels. Arteries carry blood away from the heart, veins carry blood back to the heart, and capillaries are tiny vessels where substances are exchanged with tissues.

Exam Focus: Learn the enzyme names and what they break down - this comes up frequently in tests!

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Disease and Defence

Pathogens are microorganisms that cause disease, and they come in four main types. Bacteria reproduce rapidly and release toxins, viruses live inside cells and damage them, fungi grow and spread on organisms, and protists are parasites that live off other organisms.

Your body has brilliant defence mechanisms against disease. Physical barriers like skin, hair, and mucus stop pathogens entering. If they do get in, white blood cells either consume the invaders or produce antibodies that attack specific pathogens.

Vaccination works by injecting small amounts of dead or inactive pathogens, making your immune system familiar with the disease so it can fight it off quickly if you encounter it again. Antibiotics kill bacteria but don't work against viruses - that's why doctors won't give them for colds or flu.

Real World: Antibiotic-resistant bacteria develop when people don't complete their antibiotic courses, so always finish the full prescription!

Biology paper 1 foundation & higher – page 4

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Respiration and Photosynthesis

Respiration happens in every living cell to transfer energy from glucose - it's how your body powers everything from muscle contractions to maintaining body temperature. Aerobic respiration uses oxygen and happens in the mitochondria, whilst anaerobic respiration happens without oxygen but only provides energy for short periods.

Photosynthesis is how plants make their own food using the equation: 6CO₂ + 6H₂O + light energy → C₆H₁₂O₆ + 6O₂. Plants use the glucose produced for respiration, making cellulose for structure, or storing it as starch for later.

The rate of photosynthesis depends on limiting factors - whichever factor is in shortest supply limits the whole process. These are light intensity, carbon dioxide concentration, and temperature. Farmers use greenhouses to control these factors and maximise crop growth.

Memory Trick: Photosynthesis and respiration are basically opposite processes - one makes glucose using CO₂, the other breaks down glucose producing CO₂!

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