DNA and genetics might seem complex, but they're actually the... Show more
Sign up to see the contentIt's free!
Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Subjects
Responding to change (a2 only)
Infection and response
Homeostasis and response
Energy transfers (a2 only)
Cell biology
Organisms respond to changes in their internal and external environments (a-level only)
Biological molecules
Organisation
Substance exchange
Bioenergetics
Genetic information & variation
Inheritance, variation and evolution
Genetics & ecosystems (a2 only)
Ecology
Cells
Show all topics
1l the quest for political stability: germany, 1871-1991
Britain & the wider world: 1745 -1901
The cold war
Inter-war germany
Medieval period: 1066 -1509
2d religious conflict and the church in england, c1529-c1570
2o democracy and nazism: germany, 1918-1945
1f industrialisation and the people: britain, c1783-1885
1c the tudors: england, 1485-1603
2m wars and welfare: britain in transition, 1906-1957
World war two & the holocaust
2n revolution and dictatorship: russia, 1917-1953
2s the making of modern britain, 1951-2007
World war one
Britain: 1509 -1745
Show all topics

8
0
hannah
27/11/2025
Biology
B6~ inheritance, variation & evolution
244
•
27 Nov 2025
•
hannah
@hannah_qhgof
DNA and genetics might seem complex, but they're actually the... Show more








Ever wondered why you've got your dad's nose or your gran's curly hair? It all comes down to DNA - the chemical blueprint stored in long molecules called chromosomes. Think of DNA as a massive instruction manual that determines every inherited characteristic you have.
Genes are like individual recipes within this manual. Each gene is a small section of DNA that codes for a specific protein by arranging amino acids in particular sequences. With just 20 different amino acids, your body creates thousands of unique proteins!
Your genome is your complete genetic collection - like having every recipe book ever written just for you. Scientists studying the human genome can now identify disease-linked genes and trace how populations migrated across the globe.
Key Point: Understanding your genome is like having a personalised health manual - it helps predict inherited diseases and develop targeted treatments.

Reproduction comes in two main flavours, and each has massive consequences for genetic diversity. Sexual reproduction combines genetic material from two parents through fertilisation - when an egg and sperm fuse together. Each parent contributes 23 chromosomes through gametes (sex cells), creating offspring with a full set of 46 chromosomes.
This mixing creates variation - why siblings aren't identical (unless they're twins). It's nature's way of ensuring species can adapt and survive changing environments.
Asexual reproduction tells a completely different story. With only one parent involved, offspring are genetic clones - identical copies created through mitosis. No gamete fusion means no chromosome mixing and zero variation.
Remember This: Sexual reproduction = variation and adaptability. Asexual reproduction = quick colonisation but vulnerability to diseases.

Meiosis is the special cell division that creates gametes with exactly half the normal chromosome number. It's like shuffling a deck of cards - chromosomes get mixed up randomly, ensuring each gamete is genetically unique.
The process involves chromosome pairs lining up, separating, then dividing again. This produces four genetically different gametes from one original cell. When fertilisation occurs, mitosis takes over to build the embryo through repeated cell divisions.
Genetic diagrams help predict inheritance patterns using alleles - different versions of the same gene. You inherit two alleles for each characteristic (one from each parent). Dominant alleles (shown as capital letters) mask recessive alleles (lowercase letters). Your genotype is your allele combination, whilst your phenotype is the actual characteristic you display.
Quick Tip: Remember - you need two recessive alleles to show a recessive trait, but only one dominant allele to show a dominant trait.

Mutations are random DNA changes that create new genetic variants. Most mutations barely affect you, but occasionally they dramatically alter characteristics - like causing cystic fibrosis through faulty salt and water transport proteins.
Natural selection drives evolution through "survival of the fittest." Organisms best suited to their environment survive, reproduce, and pass on beneficial genes. Over generations, these advantageous characteristics become common throughout the species.
Speciation occurs when populations change so much they can't interbreed anymore - essentially becoming new species. Meanwhile, extinction happens when species can't adapt fast enough to environmental changes, new diseases, or competition.
Evolution Insight: It's not about being strongest or fastest - it's about being best adapted to your specific environment.

Selective breeding lets humans play evolution - choosing organisms with desirable traits and breeding them together over generations. Farmers use this to increase milk production, improve disease resistance, or develop gentler temperaments in animals.
However, selective breeding reduces the gene pool (available genetic diversity). This inbreeding increases risks of genetic defects and makes populations vulnerable to new diseases.
Genetic engineering takes a more direct approach - transferring specific genes between organisms using vectors like viruses or bacterial plasmids. Scientists have created bacteria producing human insulin, crops resistant to herbicides, and sheep producing medicinal compounds in their milk.
Breeding Balance: Selective breeding improves desired traits but genetic engineering offers precision - though both raise important ethical questions about manipulating life.

Fossils provide crucial evidence for evolution - showing how organisms looked millions of years ago and how they've changed. They form through mineral replacement, casts in hardened clay, or preservation in amber, ice, or acidic peat bogs where decay can't occur.
Antibiotic-resistant bacteria demonstrate evolution in action. Random mutations occasionally make bacteria less affected by antibiotics. Since bacteria reproduce rapidly, resistant strains quickly dominate populations when antibiotics kill off non-resistant competitors.
MRSA represents a dangerous "superbug" - resistant to most known antibiotics and particularly threatening in hospitals. Overuse and misuse of antibiotics accelerates this resistance, whilst incomplete antibiotic courses leave surviving bacteria to develop further resistance.
Resistance Reality: Taking your full antibiotic course isn't just good advice - it's crucial for preventing the next generation of superbugs.

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
605
10
App Store
Google Play
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
hannah
@hannah_qhgof
DNA and genetics might seem complex, but they're actually the fascinating instructions that make you unique! From how you inherit your mum's eyes to why some bacteria resist antibiotics, understanding genetics helps explain the incredible diversity of life around us.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Ever wondered why you've got your dad's nose or your gran's curly hair? It all comes down to DNA - the chemical blueprint stored in long molecules called chromosomes. Think of DNA as a massive instruction manual that determines every inherited characteristic you have.
Genes are like individual recipes within this manual. Each gene is a small section of DNA that codes for a specific protein by arranging amino acids in particular sequences. With just 20 different amino acids, your body creates thousands of unique proteins!
Your genome is your complete genetic collection - like having every recipe book ever written just for you. Scientists studying the human genome can now identify disease-linked genes and trace how populations migrated across the globe.
Key Point: Understanding your genome is like having a personalised health manual - it helps predict inherited diseases and develop targeted treatments.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Reproduction comes in two main flavours, and each has massive consequences for genetic diversity. Sexual reproduction combines genetic material from two parents through fertilisation - when an egg and sperm fuse together. Each parent contributes 23 chromosomes through gametes (sex cells), creating offspring with a full set of 46 chromosomes.
This mixing creates variation - why siblings aren't identical (unless they're twins). It's nature's way of ensuring species can adapt and survive changing environments.
Asexual reproduction tells a completely different story. With only one parent involved, offspring are genetic clones - identical copies created through mitosis. No gamete fusion means no chromosome mixing and zero variation.
Remember This: Sexual reproduction = variation and adaptability. Asexual reproduction = quick colonisation but vulnerability to diseases.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Meiosis is the special cell division that creates gametes with exactly half the normal chromosome number. It's like shuffling a deck of cards - chromosomes get mixed up randomly, ensuring each gamete is genetically unique.
The process involves chromosome pairs lining up, separating, then dividing again. This produces four genetically different gametes from one original cell. When fertilisation occurs, mitosis takes over to build the embryo through repeated cell divisions.
Genetic diagrams help predict inheritance patterns using alleles - different versions of the same gene. You inherit two alleles for each characteristic (one from each parent). Dominant alleles (shown as capital letters) mask recessive alleles (lowercase letters). Your genotype is your allele combination, whilst your phenotype is the actual characteristic you display.
Quick Tip: Remember - you need two recessive alleles to show a recessive trait, but only one dominant allele to show a dominant trait.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Mutations are random DNA changes that create new genetic variants. Most mutations barely affect you, but occasionally they dramatically alter characteristics - like causing cystic fibrosis through faulty salt and water transport proteins.
Natural selection drives evolution through "survival of the fittest." Organisms best suited to their environment survive, reproduce, and pass on beneficial genes. Over generations, these advantageous characteristics become common throughout the species.
Speciation occurs when populations change so much they can't interbreed anymore - essentially becoming new species. Meanwhile, extinction happens when species can't adapt fast enough to environmental changes, new diseases, or competition.
Evolution Insight: It's not about being strongest or fastest - it's about being best adapted to your specific environment.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Selective breeding lets humans play evolution - choosing organisms with desirable traits and breeding them together over generations. Farmers use this to increase milk production, improve disease resistance, or develop gentler temperaments in animals.
However, selective breeding reduces the gene pool (available genetic diversity). This inbreeding increases risks of genetic defects and makes populations vulnerable to new diseases.
Genetic engineering takes a more direct approach - transferring specific genes between organisms using vectors like viruses or bacterial plasmids. Scientists have created bacteria producing human insulin, crops resistant to herbicides, and sheep producing medicinal compounds in their milk.
Breeding Balance: Selective breeding improves desired traits but genetic engineering offers precision - though both raise important ethical questions about manipulating life.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Fossils provide crucial evidence for evolution - showing how organisms looked millions of years ago and how they've changed. They form through mineral replacement, casts in hardened clay, or preservation in amber, ice, or acidic peat bogs where decay can't occur.
Antibiotic-resistant bacteria demonstrate evolution in action. Random mutations occasionally make bacteria less affected by antibiotics. Since bacteria reproduce rapidly, resistant strains quickly dominate populations when antibiotics kill off non-resistant competitors.
MRSA represents a dangerous "superbug" - resistant to most known antibiotics and particularly threatening in hospitals. Overuse and misuse of antibiotics accelerates this resistance, whilst incomplete antibiotic courses leave surviving bacteria to develop further resistance.
Resistance Reality: Taking your full antibiotic course isn't just good advice - it's crucial for preventing the next generation of superbugs.

Access to all documents
Improve your grades
Join milions of students
By signing up you accept Terms of Service and Privacy Policy
Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.
You can download the app from Google Play Store and Apple App Store.
That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.
8
Smart Tools NEW
Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines
Explore comprehensive knowledge organisers for AQA GCSE Biology, covering essential topics such as cell structure, genetics, ecosystems, and human biology. These concise summaries are designed to enhance your understanding and retention of key concepts, making them perfect for revision and exam preparation.
Comprehensive summary of AQA Biology Paper 2 covering key concepts in inheritance, variation, evolution, genetics, homeostasis, and ecology. This resource includes essential details on protein synthesis, inherited disorders, the menstrual cycle, and the nervous system, making it ideal for exam preparation.
Comprehensive checklist covering all key topics in Edexcel GCSE (9-1) Combined Science, including biology, chemistry, and physics. This resource is designed to aid students in their revision by providing a structured outline of essential concepts such as hormonal control, energy transfers, and the periodic table. Ideal for exam preparation and understanding core scientific principles.
AQA
Explore the key differences between asexual and sexual reproduction, including advantages and disadvantages of each method. This summary covers essential concepts such as genetic variation, reproduction processes in plants and animals, and examples of organisms that utilize both strategies. Ideal for biology students seeking to understand reproductive mechanisms.
Explore the intricacies of human and plant reproduction in this comprehensive summary. Key topics include the male and female reproductive systems, fertilization processes, the menstrual cycle, DNA inheritance, and the differences between asexual and sexual reproduction. Ideal for GCSE Biology students seeking to understand reproductive mechanisms and genetic principles.
605
10
App Store
Google Play
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user
The app is very easy to use and well designed. I have found everything I was looking for so far and have been able to learn a lot from the presentations! I will definitely use the app for a class assignment! And of course it also helps a lot as an inspiration.
Stefan S
iOS user
This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.
Samantha Klich
Android user
Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.
Anna
iOS user
Best app on earth! no words because it’s too good
Thomas R
iOS user
Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.
Basil
Android user
This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.
David K
iOS user
The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!
Sudenaz Ocak
Android user
In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.
Greenlight Bonnie
Android user
very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.
Rohan U
Android user
I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.
Xander S
iOS user
THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮
Elisha
iOS user
This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now
Paul T
iOS user