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AQA A-Level Transport Across Cell Membranes Comprehensive Notes

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cait @caittt

Ever wonder how your cells decide what gets in and what stays out? Cell membranes are like incredibly... Show more

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

The Fluid-Mosaic Model

Think of your cell membrane as a flexible sandwich made mostly of phospholipids arranged in a double layer (bilayer). These phospholipids have water-loving heads and water-hating tails, which creates a perfect barrier that's both protective and functional.

Floating within this phospholipid bilayer are various proteins that act like doorways and transporters. Peripheral proteins sit on the surface, whilst integral proteins span right through the membrane, often serving as channels or pumps for moving substances across.

You'll also find glycoproteins and glycolipids decorating the outside surface like name tags - these help cells recognise each other and communicate. Cholesterol molecules scattered throughout act like membrane stabilisers, keeping everything at just the right consistency regardless of temperature changes.

Key Point The membrane is "fluid" because molecules can move around, and "mosaic" because it's made up of many different components working together!

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

Transport Types and Diffusion

Cell transport comes in two main flavours passive transport (no energy required) and active transport (energy needed). Diffusion is the star of passive transport - it's simply particles moving from crowded areas to less crowded ones, like people spreading out in a room.

The membrane's semi-permeability means it's picky about what passes through. Small, nonpolar molecules like oxygen slip through easily, whilst small polar molecules like water need a bit more effort. Large molecules and ions typically require special protein channels to get across.

Osmosis is diffusion's water-focused cousin - it's specifically about water moving through membranes towards areas with higher solute concentration. This creates different scenarios isotonic (balanced), hypotonic (water rushes in), and hypertonic (water leaves the cell).

Remember Plant cells handle water pressure better than animal cells because of their rigid cell walls - they can become turgid without bursting!

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

Active Transport and Diffusion Factors

Sometimes cells need to move substances against the concentration gradient - from low to high concentration areas. This is where active transport comes in, using energy from ATP to power the process through specialised protein pumps.

Co-transport is a clever system where two substances hitchhike together across the membrane. Symport moves them in the same direction, whilst antiport sends them in opposite directions - like the sodium-glucose transport in your intestines that helps absorb nutrients.

Several factors affect how quickly diffusion happens concentration gradient (the driving force), surface area to volume ratio, distance, temperature, and the number of available channel proteins. Fick's law neatly summarises this - faster diffusion occurs with larger surface areas and concentration differences, but slows down over longer distances.

Exam Tip Remember that active transport always requires energy and moves substances uphill against their natural flow - think of it as cellular weightlifting!

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Biology

102

4 Dec 2025

3 pages

AQA A-Level Transport Across Cell Membranes Comprehensive Notes

user profile picture

cait

@caittt

Ever wonder how your cells decide what gets in and what stays out? Cell membranes are like incredibly smart bouncers at a club - they're selective about who passes through and use different methods to control the flow of substances... Show more

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

Sign up to see the contentIt's free!

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The Fluid-Mosaic Model

Think of your cell membrane as a flexible sandwich made mostly of phospholipids arranged in a double layer (bilayer). These phospholipids have water-loving heads and water-hating tails, which creates a perfect barrier that's both protective and functional.

Floating within this phospholipid bilayer are various proteins that act like doorways and transporters. Peripheral proteins sit on the surface, whilst integral proteins span right through the membrane, often serving as channels or pumps for moving substances across.

You'll also find glycoproteins and glycolipids decorating the outside surface like name tags - these help cells recognise each other and communicate. Cholesterol molecules scattered throughout act like membrane stabilisers, keeping everything at just the right consistency regardless of temperature changes.

Key Point: The membrane is "fluid" because molecules can move around, and "mosaic" because it's made up of many different components working together!

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

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Transport Types and Diffusion

Cell transport comes in two main flavours: passive transport (no energy required) and active transport (energy needed). Diffusion is the star of passive transport - it's simply particles moving from crowded areas to less crowded ones, like people spreading out in a room.

The membrane's semi-permeability means it's picky about what passes through. Small, nonpolar molecules like oxygen slip through easily, whilst small polar molecules like water need a bit more effort. Large molecules and ions typically require special protein channels to get across.

Osmosis is diffusion's water-focused cousin - it's specifically about water moving through membranes towards areas with higher solute concentration. This creates different scenarios: isotonic (balanced), hypotonic (water rushes in), and hypertonic (water leaves the cell).

Remember: Plant cells handle water pressure better than animal cells because of their rigid cell walls - they can become turgid without bursting!

3.2.3 Transport across cell membranes
fluid-mosaic model of membrane structure
Globular
protein
CELL MEMBRANE
Glycoprotein Carbohydrate
Alph

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Active Transport and Diffusion Factors

Sometimes cells need to move substances against the concentration gradient - from low to high concentration areas. This is where active transport comes in, using energy from ATP to power the process through specialised protein pumps.

Co-transport is a clever system where two substances hitchhike together across the membrane. Symport moves them in the same direction, whilst antiport sends them in opposite directions - like the sodium-glucose transport in your intestines that helps absorb nutrients.

Several factors affect how quickly diffusion happens: concentration gradient (the driving force), surface area to volume ratio, distance, temperature, and the number of available channel proteins. Fick's law neatly summarises this - faster diffusion occurs with larger surface areas and concentration differences, but slows down over longer distances.

Exam Tip: Remember that active transport always requires energy and moves substances uphill against their natural flow - think of it as cellular weightlifting!

We thought you’d never ask...

What is the Knowunity AI companion?

Our AI Companion is a student-focused AI tool that offers more than just answers. Built on millions of Knowunity resources, it provides relevant information, personalised study plans, quizzes, and content directly in the chat, adapting to your individual learning journey.

Where can I download the Knowunity app?

You can download the app from Google Play Store and Apple App Store.

Is Knowunity really free of charge?

That's right! Enjoy free access to study content, connect with fellow students, and get instant help – all at your fingertips.

2

Smart Tools NEW

Transform this note into: ✓ 50+ Practice Questions ✓ Interactive Flashcards ✓ Full Mock Exam ✓ Essay Outlines

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Quiz
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Explore the intricacies of cell structure and function, including the roles of organelles, the plasma membrane, and mechanisms of transport such as diffusion, osmosis, and active transport. This summary covers key concepts like tonicity, osmoregulation, and the fluid mosaic model, essential for understanding cellular processes in AP/College Biology.

BiologyBiology
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Plasma Membrane Structure

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Stefan S

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Samantha Klich

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Best app on earth! no words because it’s too good

Thomas R

iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

Basil

Android user

This app has made me feel so much more confident in my exam prep, not only through boosting my own self confidence through the features that allow you to connect with others and feel less alone, but also through the way the app itself is centred around making you feel better. It is easy to navigate, fun to use, and helpful to anyone struggling in absolutely any way.

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

very reliable app to help and grow your ideas of Maths, English and other related topics in your works. please use this app if your struggling in areas, this app is key for that. wish I'd of done a review before. and it's also free so don't worry about that.

Rohan U

Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user

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Stefan S

iOS user

This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

Android user

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iOS user

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iOS user

Just amazing. Let's me revise 10x better, this app is a quick 10/10. I highly recommend it to anyone. I can watch and search for notes. I can save them in the subject folder. I can revise it any time when I come back. If you haven't tried this app, you're really missing out.

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Sudenaz Ocak

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In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

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Android user

I know a lot of apps use fake accounts to boost their reviews but this app deserves it all. Originally I was getting 4 in my English exams and this time I got a grade 7. I didn’t even know about this app three days until the exam and it has helped A LOT. Please actually trust me and use it as I’m sure you too will see developments.

Xander S

iOS user

THE QUIZES AND FLASHCARDS ARE SO USEFUL AND I LOVE THE SCHOOLGPT. IT ALSO IS LITREALLY LIKE CHATGPT BUT SMARTER!! HELPED ME WITH MY MASCARA PROBLEMS TOO!! AS WELL AS MY REAL SUBJECTS ! DUHHH 😍😁😲🤑💗✨🎀😮

Elisha

iOS user

This apps acc the goat. I find revision so boring but this app makes it so easy to organize it all and then you can ask the freeeee ai to test yourself so good and you can easily upload your own stuff. highly recommend as someone taking mocks now

Paul T

iOS user